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Autophagy: Biology and Diseases
This book consists of 3 volumes: Basic Science (Volume 1), Clinical Science (Volume 2) and Technology and Methodology (Volume 3). Volume 2 focuses on the clinical aspects of autophagy research, discussing the role of autophagy in neuropsychiatric disorders, the cardiovascular, immune, digestive and endocrine systems, as well as tumors, infection, the kidney, and the respiratory and hematological systems. It also addresses autophagy-related drug development. Written and edited by a team of 90 experts, and presenting the state of the art in autophagy research, this book is a valuable reference resource for researchers and clinicians alike. It can also be used as supplementary material for graduate students majoring in biology and medicine
Black Holes
From the author of Hanging Devils, one of The Guardian's top ten Asian crime novels, comes the long-awaited follow-up. When Xia Zhe, an ambitious trader at a state-owned securities company, is indicted for corporate fraud, lawyer Hong Jun takes on the case at the request of the young man's father. But as the trial date looms, it becomes clear that this case of avarice and ill-gotten gains is far from black and white. Hong Jun discovers a web of family secrets and hidden motives leading back to the turbulence of the Cultural Revolution. What he doesn't count on is that, in dredging up these long-dormant histories, he must face the shadows of his own past to get to the truth.
Surveillance Education
Surveillance Education explores the pervasive use of digital surveillance technologies in schools and assesses its pernicious effects on students. Recognizing that the use of digital technologies will persist, the authors instead offer practical ways to ameliorate their impact. In our era of surveillance capitalism, digital media technologies are ever more intertwined into the educational process. Schools are presented with digital technologies as tools of convenience for gathering and grading student work, as tools of support to foster a more equitable learning environment, and as tools of safety for predicting or preventing violence or monitoring mental, emotional, and physical health. Des...
The Taiwan Consensus and the Ethos of Area Studies in Pax Americana
This book constitutes a timely intervention into debates over the status of Taiwan, at a moment when discussions of democracy and autocracy, imperialism and agency, unipolarity and multipolarity, dominate the intellectual agenda of the day. Pursuing a parallel trajectory that is both epistemic and historical, that is traced out in relation both to Taiwan’s recent history and to the disparate forms of knowledge production about that history, this work engages in scholarly debate about some of the burning issues of our time, including transitional justice, hegemony and conspiracy in the digital age, debt regimes, cultural difference, national language, and the traumatic legacies of war, colo...
mTOR in Human Diseases
The mechanistic target of rapamycin (mTOR) is a major signaling intermediary that coordinates favorable environmental conditions with cell growth. Indeed, as part of two functionally distinct protein complexes, named mTORC1 and mTORC2, mTOR regulates a variety of cellular processes, including protein, lipid, and nucleotide synthesis, as well as autophagy. Over the last two decades, major molecular advances have been made in mTOR signaling and have revealed the complexity of the events implicated in mTOR function and regulation. In parallel, the role of mTOR in diverse pathological conditions has also been identified, including in cancer, hamartoma, neurological, and metabolic diseases. Through a series of articles, this book focuses on the role played by mTOR in cellular processes, metabolism in particular, and highlights a panel of human diseases for which mTOR inhibition provides or might provide benefits. It also addresses future studies needed to further characterize the role of mTOR in selected disorders, which will help design novel therapeutic approaches. It is therefore intended for everyone who has an interest in mTOR biology and its application in human pathologies.
Daily Report
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