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This is the third edition of a comprehensive study of the neuronal disorders of the lower gastrointestinal tract in children. Important new studies and progress in research on bowel motility and motility disorders are covered in detail as well as new aspects concerning the embryology, functional anatomy of the enteric nervous system. In particular new insights have been received from the studies in the genetics of Hirschsprung's disease. Special emphasis is laid on new surgical techniques, especially on the laparoscopic approach in combination with Soave's or Duhamel's technique.
The survival rate of childhood cancer has increased remarkably in the past three decades, yet prolonged delay in diagnosis of pediatric cancer is still a major challenge. The genetics and biology of pediatric cancer are distinct from those of adult cancer. A growing number of predictive, diagnostic, therapeutic and prognostic biomarkers have been identified at a genomic, transcriptomic, proteomic, metabolomic, and cellular levels. However, these identified biomarkers are mostly applied to adult cancer patients and are not optimal for pediatric cancer patients. Therefore, it remains an urgency to seek for novel biomarkers that are specifically applied to pediatric cancer. A better understandi...
Zcela unikátní monografie z pera zkušených autorů, první tohoto druhu na našem knižním trhu! Postgraduální učebnice, kterou ocení nejen gastroenterologové, ale i chirurgové, internisté, pediatři a další související obory.