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Understanding Novelty in Organizations
Providing a first tentative understanding of novelty and a set of implications for organizations to manage it, this book focuses on the potential offered by emergent novelty, namely novelty which is neither designed nor pursued. The author asks how organizations might increase their abilities and strategies to benefit from its early recognition. Such potential is broken down into positive terms and demonstrates how early recognition is beneficial both to organizations which aim to seize emergent innovations as well as those which aim to avoid emergent disasters. Understanding Novelty in Organizations aims to rethink the structure and strategies of organizations to gain a new balance between design and randomness in the generation of novelty. The varied perspectives presented in this work will engage scholars interested in novelty, innovation and creativity, and emergency management.
The Open Innovation Marketplace
Many technical obstacles to effective innovation no longer exist: today, companies possess global networks that can connect with knowledge from virtually any source. Today’s challenge is to collaboratively transform that knowledge into higher-value innovation. Their book introduces groundbreaking strategies and models for consistently achieving this goal. Authors Alpheus Bingham and Dwayne Spradlin draw on their own experience building InnoCentive, the pioneering global platform for open innovation (a.k.a. "crowdsourcing"). Writing for business executives, R&D leaders, and innovation strategists, Bingham and Spradlin demonstrate how to dramatically increase the flow of high-value ideas and...
The Long Tail of Expertise
This Element is an excerpt from The Open Innovation Marketplace: Creating Value in the Challenge Driven Enterprise (9780132311830) by Alpheus Bingham and Dwayne Spradlin. Available in print and digital formats. Use the “long tail” concept to find high-value innovation and expertise where you never expected it. The Long Tail concept has found applications in marketing, inventory, and beyond. We invoke it to illustrate observations broadly applicable to innovation and to expertise in general. Though I’m not an “expert plumber,” I do know more than many people; and others know more than me, but may still not quite be “experts.” These definitions are continuous: no bright boundary line exists…
Exploring the Biological Contributions to Human Health
It's obvious why only men develop prostate cancer and why only women get ovarian cancer. But it is not obvious why women are more likely to recover language ability after a stroke than men or why women are more apt to develop autoimmune diseases such as lupus. Sex differences in health throughout the lifespan have been documented. Exploring the Biological Contributions to Human Health begins to snap the pieces of the puzzle into place so that this knowledge can be used to improve health for both sexes. From behavior and cognition to metabolism and response to chemicals and infectious organisms, this book explores the health impact of sex (being male or female, according to reproductive organ...
Successful OSS Project Design and Implementation
The open source phenomenon has attracted an increased interest among commercial firms and governments. It is becoming one of the most influential paradigm shifts not only in software development but in social and economic value creation as well. While software development is perhaps the most prominent example of open source, its principles have now been applied across a wide range of product classes, industries and even scientific disciplines. Decision makers at different levels and in a variety of fields need to improve their understanding of the factors that contribute to the Open Source Software (OSS) effectiveness: approaches, tools, social designs, reward structures and metrics. Successful OSS Project Design and Implementation provides a state-of-the-art analysis of OSS design principles, their emergence and success and how they are extending well beyond the domain of software.
Revealing Architectural Design
Revealing Architectural Design examines the architectural design process from the point of view of knowledge domains, domain syntax, coherence, framing, thinking styles, decision-making and testing. Using straightforward language, the book connects general design thinking to underlying frameworks that are used in the architectural design process. The book provides historical grounding as well as clear examples of real design outcomes. It includes diagrams and explanations to make that content accessible. The frameworks and their methods are described by what they can accomplish, what biases they introduce and the use of their final outcomes. Revealing Architectural Design is an advanced primer useful to anyone interested in increasing the quality of their architectural design proposals through understanding the conceptual tools used to achieve that process. While it is intended for undergraduate and graduate students of architectural design, it will also be useful for experienced architectural practitioners. For the non-architect, this book opens a window into the priorities of a discipline seldom presented with such transparency.
The Neurobiology of NO· and ·OH
This work reflects the current interest in the free radical, nitric oxide, and the hydroxyl radical, which is probably the most reactive oxidant in the human body. The molecular mechanisms underlying neurodegeneration and brain disorders are discussed along with possible future therapeutic strategies for countering these pathologic conditions. The book covers novel transmitter roles, generation and detection of reactive oxygen species in the central nervous system, the role of free radicals in neural transmission, antioxidant defence mechanisms, transgenic animal models, and new chemical antioxidants for protecting brain neurons. This volume should be read by those interested in the ageing of the CNS, Parkinson's disease, Alzheimer's dementia, Down's syndrome, head trauma and stroke.
Managing Networks of Creativity
The aim of the Managing Networks of Creativity is to improve our understanding of creativity and the management of creativity, as discussed in the fields of management (including strategic management, organization science, organizational behaviour, and entrepreneurship), economics, sociology, regional studies, and political science. While research on creativity has made several important contributions to the theoretical literature, little attention has been paid to the development and testing of formal theoretical models, especially in those cases where creativity is the result not so much of individual behaviour than the outcome of collective efforts, connecting individuals in organizations...
Better Together
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Drug Repositioning
The how's and why's of successful drug repositioning Drug repositioning, also known as drug reprofiling or repurposing, has become an increasingly important part of the drug development process. This book examines the business, technical, scientific, and operational challenges and opportunities that drug repositioning offers. Readers will learn how to perform the latest experimental and computational methods that support drug repositioning, and detailed case studies throughout the book demonstrate how these methods fit within the context of a comprehensive drug repositioning strategy. Drug Repositioning is divided into three parts: Part 1, Drug Repositioning: Business Case, Strategies, and O...
