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As the aging population degree is deepened, cognitive impairment has become a globally recognized public health problem. As an intermediate state from normal cognition (NC) to Alzheimer's disease (AD), mild cognitive impairment (MCI) has a highly variable cognitive trajectory, which contains three outcomes: 1) progression to AD and other types of dementia; 2) Maintaining stability; 3) Reversal to NC. Reversal of cognitive function can be achieved by taking positive and effective measures. Current studies mostly focus on factors affecting MCI to AD. World Health Organization and Alzheimer’s Disease International have also proposed relatively mature guidelines for risk factors. However, ther...
Dr. Dorsen, a fellow in the American College of Sports Medicine and retired internist, is a cum laude graduate from Dartmouth College with his medical degree from the Rutgers New Jersey University School of Medicine, and residencies in medicine at Johns Hopkins and Hennepin County Hospital Minneapolis, Minnesota. He has served at the United States Paralympic and Olympic Training Center in Colorado Springs, and as a team physician for the U.S. Olympic Cross Country Ski Team. He is the author of The Vikings Change the Play Against Alcohol and Other Dangerous Drugs; Dr. D’s Handbook for Men Over 40: A Guide to Health, Fitness, Living, and Loving in the Prime of Life; Up from the Ashes: One Do...
This book is a comprehensive guide to the diagnosis and management of both common and rare neurological disorders, for practising neurologists and trainees. Divided into twelve chapters, each section is dedicated to a subspecialty of neurology, including movement disorders, headache, epilepsy, neurotoxicology, stroke and more. Topics are presented with a broad overview and include recent advances in the field. Content is further enhanced by tables, clinical images, boxes and flow charts to assist learning. Key points Comprehensive guide to neurological disorders for clinicians and trainees Each section dedicated to a subspecialty of neurology Includes recent advances in the field Highly illustrated with tables, clinical images, boxes and flow charts
Advances in healthcare have led to an extended life expectancy throughout the developed world, but cognitive impairment in later life, and Alzheimer's disease (AD) in particular, remains one of the intractable problems which can blight quality of life as we age. Depression in Alzheimer's disease is an additional factor which has a significant impact on disability, disease progression, and caregiver burden. This book, volume 4 of the Advances in Alzheimer’s Disease book series which is published in coordination with the Journal of Alzheimer’s Disease, presents papers which reflect the progress in recent years of research into depression in AD. This research has focused on several areas, i...
This book involves the design, analysis, and application of various cognitive predictive maintenance tests with the help of tools like vibration analysis, ultrasonic analysis, infrared analysis, oil analysis, laser-shaft alignment, and motor circuit analysis in the prediction of various cognitive diseases such as epilepsy, Parkinson’s disease, Alzheimer’s disease, and depression. These are needed since there are no proper medical tests available to predict these diseases in remote areas at an early stage. Various emerging technologies are analyzed for the design of tests. Key features: Incorporates innovative processes for treating cognitive diseases. Early and exact identification and t...
Volume 56 in the internationally acclaimed Advances in Clinical Chemistry contains chapters submitted from leading experts from academia and clinical laboratory science. Authors are from a diverse field of clinical chemistry disciplines and diagnostics, ranging from basic biochemical exploration to cutting-edge microarray technology. - Written by authors representing the diverse field of clinical chemistry and diagnostics, reviews in Advances in Clinical Chemistry cover a range of cutting-eduge research ranging from basic biochemical exploration to microarray technology
The Annotations on the Waterway Classic (Chinese: 水经注; pinyin: Shuǐ Jīng Zhù) is a work on the ancient geography of China, describing the traditional understanding of its waterways and ancient canals, compiled by Li Daoyuan during the Northern Wei Dynasty (386-534 AD). The book is divided into sections by river, each described with its source, course, and major tributaries, including cultural and historical notes. The work is much expanded from its source text, the older (and now lost) Waterway Classic (Shuijing 水经). The original text described 137 different rivers in China, and its authorship was attributed to Jin dynasty scholar Guo Pu. Li Daoyuan's 40-volume, 300,000-character version includes 1252 rivers.
Zi Zhi Tong Jian (Chinese: 资治通鉴;English: "Comprehensive Mirror in Aid of Governance") is a pioneering reference work in Chinese historiography, published in 1084 in the form of a chronicle. In 1065 AD, Emperor Yingzong of Songordered the great historian Sima Guang (1019–1086 AD) to lead with other scholars such as his chief assistants Liu Shu, Liu Ban and Fan Zuyu, the compilation of a universal history of China. The task took 19 years to be completed,and, in 1084 AD, it was presented to his successor Emperor Shenzong of Song. The Zi Zhi Tong Jian records Chinese history from 403 BC to 959 AD, covering 16 dynasties and spanning across almost 1,400 years,and contains 294 volumes (...
It is almost 120 years since Alzheimer’s disease (AD) was first reported, and the concept of managing some of the modifiable risk factors associated with the disease has been present from the outset. Intervening to manage risk factors as a way of tackling AD is not new, but optimizing brain health as a way of minimizing risk and maximizing the potential benefits of revolutionary new treatments for AD is becoming increasingly important. This book, the Handbook of Intervention and Alzheimer’s Disease, presents 47 papers exploring factors which may either inspire or inform future treatment and clinical trials. While novel interventions such as anti-amyloid immunotherapy present great opport...