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Biodegradability Prediction
Biodegradation is the dominant pathway for the environmental transformation of most chemicals and information on a chemical's biodegradability is essential for proper risk assessment. But there are few methods for predicting whether or not a chemical is biodegradable, since this depends on the chemical's structure as well as on the environmental conditions that it encounters.
Advanced Methods in Structural Biology
This volume explores the latest integrated bioprocesses and technologies used to study the production of the target recombinant protein of therapeutic or diagnostic interest; its isolation, purification, and stabilization; and the bio-interaction and structural analyses. The chapters in this book are organized into four parts. Part One covers production methods of soluble and membrane proteins in prokaryotic and eukaryotic expression systems, such as Lactococcus lactis and Escherichia coli. Part Two describes traditional and novel approaches for recombinant protein purification and stabilization, and buffers and additives. Part Three discusses automated methods in structural biology based on...
Enzyme Functionality
Enzyme Functionality serves as a conduit for trailblazing research in enzyme engineering-relating current understanding of sequence families, the new notion of enzyme structure classes, and modern methods in protein engineering, design, and directed evolution to accelerate the development of novel enzyme functionalities. This reference gathers the
11th International Conference on Practical Applications of Computational Biology & Bioinformatics
Biological and biomedical research are increasingly driven by experimental techniques that challenge our ability to analyse, process and extract meaningful knowledge from the underlying data. The impressive capabilities of next-generation sequencing technologies, together with novel and constantly evolving, distinct types of omics data technologies, have created an increasingly complex set of challenges for the growing fields of Bioinformatics and Computational Biology. The analysis of the datasets produced and their integration call for new algorithms and approaches from fields such as Databases, Statistics, Data Mining, Machine Learning, Optimization, Computer Science and Artificial Intell...
The Ecology of Mycobacteria: Impact on Animal's and Human's Health
habitats and the overlapping of these biotopes by humans and animals contributed to the spread of mycobacteria and perhaps to their convergence to pathogenicity. It was not our intention to present a compendium covering all published results, but rather to issue a “readable” book, which is illustrative and thus focused on the principle facts. The increase in the number of Editors has allowed the sharing of original experiences regarding the ecology of mycobacteria, published here for the ?rst time in some cases. The supplemented edition should serve as a guide to these discoveries and also contribute to an understanding of clinically signi?cant species in human and animal medicine. Borst...
Biological Crystallization
For at least six hundred million years, life has been a fascinating laboratory of crystallization, referred to as biomineralization. During this huge lapse of time, many organisms from diverse phyla have developed the capability to precipitate various types of minerals, exploring distinctive pathways for building sophisticated structural architectures for different purposes. The Darwinian exploration was performed by trial and error, but the success in terms of complexity and efficiency is evident. Understanding the strategies that those organisms employ for regulating the nucleation, growth, and assembly of nanocrystals to build these sophisticated devices is an intellectual challenge and a...
Linguistic Bibliography for the Year 2000 / Bibliographie Linguistique de l'Année 2000
Bibliographie Linguistique/ Linguistic Bibliography is the annual bibliography of linguistics published by the Permanent International Committee of Linguists under the auspices of the International Council of Philosophy and Humanistic Studies of UNESCO. With a tradition of more than fifty years (the first two volumes, covering the years 1939-1947, were published in 1949-1950), Bibliographie Linguistique is by far the most comprehensive bibliography in the field. It covers all branches of linguistics, both theoretical and descriptive, from all geographical areas, including less known and extinct languages, with particular attention to the many endangered languages of the world. Up-to-date information is guaranteed by the collaboration of some forty contributing specialists from all over the world. With over 20,000 titles arranged according to a detailed state-of-the-art classification, Bibliographie Linguistique remains the standard reference book for every scholar of language and linguistics.
Biodegradative Bacteria
Biodegradative Bacteria highlights the novel nature of bacterial cell functions in the field of biodegradation by putting them into three parts: (1) Genetic and genomic systems, (2) Degradative enzyme systems, and (3) Bacterial behavior in natural environmental systems. The first part of the book includes cell functions as degradative machinery, genome systems for effective degradation, and the evolution of degradative systems by mobile genetic elements. The second part deals with the structure, function, evolution, diversity, and application of degradative and related enzymes. The third part presents cell or genomic behaviors of biodegradative bacteria in natural ecosystems. Bacterial metab...
Practical Methods for Biocatalysis and Biotransformations 2
Biocatalysts are increasingly used by chemists engaged in fine chemical synthesis within both industry and academia. Today, there exists a huge choice of high-tech enzymes and whole cell biocatalysts, which add enormously to the repertoire of synthetic possibilities. Practical Methods for Biocatalysis and Biotransformations 2 is a "how-to" guide that focuses on the practical applications of enzymes and strains of microorganisms that are readily obtained or derived from culture collections. The sources of starting materials and reagents, hints, tips and safety advice (where appropriate) are given to ensure, as far as possible, that the procedures are reproducible. Comparisons to alternative m...
Genetically Engineered Organisms in Bioremediation
Genetically Engineered Organisms in Bioremediation provides comprehensive coverage of biotechnological applications of genetically engineered microorganisms for the bioremediation of polluted environments. Chapters are contributed by international scientists with in-depth knowledge, expertise, vision and commitment in their scientific profession. They detail several genetically engineered microorganisms and their enzymes that could be applied to biologically break down persistent organic pollutants and recombinant DNA technologies which entail development of "suicidal-GEMs" for effective and safe remediation of heavily polluted sites. FEATURES: • Highlights genes that encode catabolic enzy...
