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Covers the colonial origins of the three infantry regiments that comprise the Blue and Gray Division,"" the establishment of the Division in 1917, and its current status as a light infantry division in the Maryland National Guard. Contains an emphasis on the history of the 29th Infantry Division in WWII. Map displaying activity of 29th Division from June 6, 1944 through January 1, 1945 on endsheets. Hundreds of photos. Indexed""
New Findings Revolutionize Concepts of Gene FunctionEndogenous small RNAs have been found in various organisms, including humans, mice, flies, worms, fungi, and bacteria. Furthermore, it's been shown that microRNAs acting as cellular rheostats have the ability to modulate gene expression. In higher eukaryotes, microRNAs may regulate as much as 50 p
A collection of readily reproducible methods for the design, preparation, and use of RNAs for silencing gene expression in cells and organisms. The techniques range widely and include methods addressing the biochemical aspects of the silencing machinery, RNA silencing in non-mammalian organisms, and the in vivo delivery of siRNAs and silencing vectors. There are also techniques for designing, preparing, and using RNAs to silence gene expression, for fine-tuning regulation by targeting specific isoforms of a given gene, and for the study and use of microRNAs. The protocols follow the successful Methods in Molecular BiologyTM series format, each offering step-by-step laboratory instructions, an introduction outlining the principle behind the technique, lists of the necessary equipment and reagents, and tips on troubleshooting and avoiding known pitfalls.
Presents a unified approach to parametric estimation, confidence intervals, hypothesis testing, and statistical modeling, which are uniquely based on the likelihood function This book addresses mathematical statistics for upper-undergraduates and first year graduate students, tying chapters on estimation, confidence intervals, hypothesis testing, and statistical models together to present a unifying focus on the likelihood function. It also emphasizes the important ideas in statistical modeling, such as sufficiency, exponential family distributions, and large sample properties. Mathematical Statistics: An Introduction to Likelihood Based Inference makes advanced topics accessible and underst...
This book provides a compelling overall update on current status of RNA interference
This book will provide latest insights in the functional potentials of ribonucleic acids in medine and the use of Spiegelmer and Spiegelzyme systems. It will also deal with a new type of delivery systems for cellular targeting.