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The Promises and Challenges of Regenerative Medicine
Presents the advances in stem cell research. This book discusses the analysis and use of stem cells in basic biology, and their application in clinical practice.
Stem Cells in Reproduction and in the Brain
Expectations of the potential of regenerative medicine have risen recently because of exciting research results. This book contains contributions from leading researchers who describe their successes and the problems that remain in converting the hopes into concrete therapies. The focus of the book is on the role of stem cells in two main areas -- reproduction and the brain -- described from molecular, cellular, in vivo and clinical perspectives.
Inflammatory Diseases of Blood Vessels
Inflammatory Diseases of Blood Vessels“/b> Inflammatory Diseases of Blood Vessels Second Edition Inflammatory Diseases of Blood Vessels provides a comprehensive overview of the science and clinical consequences of vascular inflammation in health and disease. In recent years, considerable progress has been made in understanding different forms of vasculitis. Investigation of pathogenesis of vascular inflammation has led to improved treatments and outcomes. Surgical and transplant procedures have improved in parallel with medical therapies. These areas are extensively examined in this new edition. Inflammatory Diseases of Blood Vessels is an excellent resource for a broad readership, including clinicians, investigators and their support teams in numerous specialties e.g. rheumatology, immunology, cardiology, cardiovascular surgery, pulmonary medicine, nephrology, pathology, vascular biology, embryology and imaging.
Proteases and Cancer
This volume details bioinformatics analysis, biochemical assays, recombinant protein expression and purification, methods to investigate protease activity in cell-based, organoids and in vivo systems, proteomics, transcriptomics, machine learning and novel approaches to target dysregulated protease activity in cancer. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Cancer Immunotherapy: Methods and Protocols aims to provide the scientific community with a diverse and representative collection of state-of-the-art methods to investigate the protean functions of proteases in cancer biology.
Interferons
Interferons documents the proceedings of a major international conference on Chemistry and Biology of Interferons: Relationship to Therapeutics held at Squaw Valley, California, in March 1982. The meeting was one of the 1982 UCLA Symposia on Molecular and Cellular Biology organized through the Molecular Biology Institute of the University of California at Los Angeles. The book is organized into four parts. Part I presents papers on recombinant DNA production of interferon. It includes studies on the synthesis of human immune interferon in E. coli and monkey cells; the expression of human ß interferon gene in heterologous cells; and the molecular activities of recombinant and hybrid leukocyt...
Controlling the Federal Bureaucracy
How do we fit bureaucracy into a democratic political system? No other question has received--or deserved--more attention from those who study public administration. While this question might receive slightly different responses, there is one common thread, the notion that bureaucrats must be subject to external controls. Who possesses the ability to influence the government from the outside? How do these people use their influence? Is their influence used to promote democratic values? Dennis Riley assesses the effect congressional committees and subcommittees have on government agencies as well as the influence of clientele groups and professional associations. The author also explores the ...
Holy Intoxication to Drunken Dissipation
On the eve of the Spanish conquest of the Inca Empire, peoples throughout the Andes brewed beer from corn and other grains, believing that this alcoholic beverage, called asua, was a gift from the gods, a drink possessing the power to mediate between the human and divine. Consuming asua to intoxication was a sacred tradition that humans and spirits shared, creating reciprocal joy and ties of mutual obligation. When Butler began research in Huaycopungo, Ecuador, in 1977, ceremonial drinking was causing hardship for these Quichua-speaking people. Then, in 1987, a devastating earthquake was interpreted as a message from God to end the ritual obligation to get drunk. Holy Intoxication to Drunken Dissipation examines how the defense of drinking and getting drunk ended abruptly as the people of Otavalo re-evaluated their traditional religious life and their relationship with the wider Ecuadorian society, and defended a renewed traditional indigenous culture with increasing pride. This account presents both the local people's views of their struggles and a more general analysis of the factors involved, and concludes with thoughts about how their culture will adapt in the future.
AHA Scientific Sessions 2016: Program Information
The American Heart Association’s Scientific Sessions 2016 is bringing big science, big technology, and big networking opportunities to New Orleans, Louisiana this November. This event features five days of the best in science and cardiovascular clinical practice covering all aspects of basic, clinical, population and translational content.
Cell Surface Proteases
Cell Surface Proteases provides a comprehensive overview of these important enzymes that catalyze the hydrolysis of a protein as it degrades to a simpler substance. In the 1990s, an explosion of new discoveries shed light on the role of cell surface proteases and extended it beyond degradation of extracellular matrix components to include its influence on growth factors, cell signaling, and other cellular events. This volume unites the scientific literature from across disciplines and teases out unified themes of interactions between cell surface proteases and interconnecting cell surface-related systems -- including integrins and other adhesion molecules. Scientists and students involved in developmental biology, cell biology and disease processes will find this an indispensable resource.* Provides an overview of the entire field of cell surface proteases in a single volume* Presents major issues and astonishing discoveries at the forefront of modern developmental biology and developmental medicine * A thematic volume in the longest-running forum for contemporary issues in developmental biology with over 30 years of coverage
