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Un Detective llamado ADNA
José Antonio Lorente, uno de los máximos especialistas en el campo de la genética, nos introduce en la investigación científica a través del ADN. Con un estilo apto para el público no especializado, el científico se adentra en el campo de la identificación genética, la estructura del genoma humano, la criminalística y las ciencias forenses (cómo resolver un crimen gracias a los testimonios genéticos), los orígenes del hombre y las distintas razas siguiendo la herencia del ADN?En uno de los capítulos, Lorente reinterpreta la historia gracias a distintas evidencias genéticas: de dónde vino Colón, la identificación del Zar Nicolás II y su familia o la historia del capitán James Cook estudiada a partir de sus genes. Este libro analiza uno de los aspectos más importantes de la genética actual: su aplicación a la identificación de desaparecidos o víctimas de accidentes. El investigador explica también en esta obra su experiencia en Nueva York tras el 11-S y en Madrid tras el 11-M, donde colaboró en la identificación de las víctimas de los atentados.
Forensic DNA Typing: Principles, Applications and Advancements
The book explores the fundamental principles, advances in forensic techniques, and its application on forensic DNA analysis. The book is divided into three modules; the first module provides the historical prospect of forensic DNA typing and introduces fundamentals of forensic DNA typing, methodology, and technical advancements, application of STRs, and DNA databases for forensic DNA profile analysis. Module 2 examines the problems and challenges encountered in extracting DNA and generating DNA profiles. It provides information on the methods and the best practices for DNA isolation from forensic biological samples and human remains like ancient DNA, DNA typing of skeletal remains and disast...
Textbook of Forensic Science
This textbook provides essential and fundamental information to modern forensics investigations. It discusses criminalistics and crime scene aspects, including investigation, management, collecting and packaging various types of physical evidence, forwarding, and chain of custody. It presents fundamental principles, ethics, challenges and criticism of forensic sciences and reviews the crime typologies, the correlates of crime, criminology, penology, and victimology. It provides a viewpoint on legal aspects, including types of evidence, the procedure in the court and scrutiny of the evidence and experts. The book summarizes forensic serological evidences such as blood, semen, saliva, milk-tea...
Epigenetics Territory and Cancer
This book explores epigenetic strategies, bridging fundamental cancer epigenetics, different paradigms in tumor genetics and translational understanding for both the clinic and improved lifestyles. The work provides target-based insights for treating different types of cancers and presents research on evolutionary epigenetics, introducing ‘Medical Epi- Anthropology’ and ‘Cancer Epi-Anthropology’. Translating multi-disciplinary research into therapeutic design is at the core of this book. Readers may explore how cancer management involves unmasking the involved networks and the interactive status of different genes to achieve the appropriate methylome based therapy. Early chapters exp...
Women in the Spanish Novel Today
This collection of new essays examines the representation of the female self in recent novels written by Spanish women. The essays explore the myriad ways in which women's struggle with self-definition and self-fulfillment is contemplated in Spain during a time in which democracy has taken hold and women's rights have taken shape. Authors covered include Carmen Martin Gaite, Josefina Aldecoa, Rosa Montero, Dulce Chacon, Clara Sanchez, Lucia Etxebarria, Care Santos, Eugenia Rico, Espido Freire, and others.
Epic, Empire, and Community in the Atlantic World
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Isolation and Molecular Characterization of Circulating Tumor Cells
Numerous studies have shown that elevated levels of circulating tumor cells (CTCs) in blood of cancer patients are associated with poor response to treatment and inferior survival probabilities. Despite this clinical significance, the molecular biology of CTCs remains poorly understood. The paucity in molecular information can be attributed to the tremendous technical challenges involved in isolating these extremely rare cells. Recent technological advancements in rare-cell technology, however, have allowed for the reliable enrichment and isolation of CTCs. Consequently, the use of recently developed molecular approaches —e.g., multiplexed QPCR, microarray, and next generation sequencing analyses— to profile CTCs have provided novel insights into the molecular makeup of these tumor cells. This book discusses approaches for enrichment and isolation of CTCs as well as recent advances in comprehensive molecular profiling of CTCs using cutting-edge omics technology.
DNA Fingerprinting: Advancements and Future Endeavors
This book describes the basics and various applications of DNA fingerprinting, including in actual case studies. The book is divided in four modules; Module 1: Basics of DNA Fingerprinting, Module 2: Applications of DNA Fingerprinting, Module 3: DNA Fingerprinting: Case Studies, and Module 4: Future of DNA Fingerprinting. Each module consists of 4 to 5 chapters, written by reputed researchers, academics and forensic scientists from around the globe. The respective chapters cover e.g. related fields, the tools and techniques used, various genotyping kits, real-world case studies, ancient DNA and wild life forensics, molecular diagnosis of human diseases, legal aspects, microbial forensics and...
Handbook of Missing Persons
This ambitious multidisciplinary volume surveys the science, forensics, politics, and ethics involved in responding to missing persons cases. International experts across the physical and social sciences offer data, case examples, and insights on best practices, new methods, and emerging specialties that may be employed in investigations. Topics such as secondary victimization, privacy issues, DNA identification, and the challenges of finding victims of war and genocide highlight the uncertainties and complexities surrounding these cases as well as possibilities for location and recovery. This diverse presentation will assist professionals in accessing new ideas, collaborating with colleague...
