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This book provides a comprehensive guide to Spain's major political and economic institutions, analysing their role, structure and functions, as well as their relationship to each other.
Describes important modelling and computational methods for systems biology research to enable practitioners to select and use the most suitable technique Systems Biology Modelling and Analysis provides an overview of state-of-the-art techniques and introduces related tools and practices to formalize models and automate reasoning for systems biology. The authors present and compare the main formal methods used in systems biology for modelling biological networks, including discussion of their advantages, drawbacks, and main applications. Each chapter includes an intuitive presentation of the specific formalism, a brief history of the formalism and of its applications in systems biology, a fo...
Este libro actualiza los conocimientos e investigaciones que se realizan en torno al alcornoque a nivel internacional desde un punto de vista integrador desde las perspectivas del árbol, el sistema en el que éste se integra y los productos que de él se generan. El libro está integrado por 42 aportaciones organizadas en 7 capítulos que comprenden la ecofisiología y genética de la especie, los modelos de crecimiento y producción, la regeneración y selvicultura, los aspectos sanitarios, la gestión multiobjetivo y sostenibilidad de los alcornocales, la producción y calidad de madera y corcho, así como aspectos relacionados con la innovación y generación de nuevos productos.
Guía que se realiza para dar cumplimiento a la Ley 11/83 de Reforma Universitaria y Decretos que la desarrollan.
This volume explores the latest methods used to study various aspects of TET proteins and their biology. Chapters in this book are divided into five parts. Part One describes technologies aimed at detecting and quantifying DNA methylation turnover using massively parallel sequencing, ELISA, and mass spectrometry approaches. Part Two looks at data analyses protocols for distinguishing acting versus passive DNA demethylation and estimation of 5mC and 5hmC levels. Part Three deals with a new topic that takes advantage of modified CRISPR/Cas9 genome editing systems to target DNA demethylation activity to genomic loci of interest. Part Four discusses protocols that detail how to purify TET protei...
For a machine to convert text into sounds that humans can understand as speech requires an enormous range of components, from abstract analysis of discourse structure to synthesis and modulation of the acoustic output. Work in the field is thus inherently interdisciplinary, involving linguistics, computer science, acoustics, and psychology. This collection of articles by leading researchers in each of the fields involved in text-to-speech synthesis provides a picture of recent work in laboratories throughout the world and of the problems and challenges that remain. By providing samples of synthesized speech as well as video demonstrations for several of the synthesizers discussed, the book will also allow the reader to judge what all the work adds up to -- that is, how good is the synthetic speech we can now produce? Topics covered include: Signal processing and source modeling Linguistic analysis Articulatory synthesis and visual speech Concatenative synthesis and automated segmentation Prosodic analysis of natural speech Synthesis of prosody Evaluation and perception Systems and applications.