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Glutamate and Neuropsychiatric Disorders
This volume provides a comprehensive overview of recent advances in targeting glutamate signaling for the treatment of major psychiatric and neurological disorders. It draws on the latest findings in glutamate neurobiology and offers valuable insights into the application of translational principles in neuroscience drug discovery and development. In each chapter, glutamate as a neurotransmitter, its receptors and transporters, and their interplay with other neurotransmitters and neurotrophic factors, are discussed in the context of a specific, highly prevalent and disabling CNS disease. Most recent and detailed information is provided on Ischemic Stroke, Chronic Stress, Major Depressive Diso...
Earthquake Research and Analysis
The mitigation of earthquake-related hazards represents a key role in the modern society. The main goal of this book is to present 9 scientific papers focusing on new research and results on earthquake seismology. Chapters of this book focus on several aspect of seismology ranging from historical earthquake analysis, seismotectonics, and damage estimation of critical facilities.
Teaching Language and Literature On and Off-Canon
Language and literature teaching are a keystone in the age of STEM, especially when dealing with minority communities. Practical methodologies for language learning are essential for bridging the cultural gap. Teaching Language and Literature On and Off-Canon is a critical research publication that provides a multidisciplinary, multimodal, and heterogenous perspectives on the applications of language learning and teaching practices for commonly studied languages, such as Spanish, English, and French, and less-studied languages, such as Latin, Gaelic, and ancient Semitic languages. Highlighting topics such as language acquisition, artistic literature, and minority languages, this book is essential for language teachers, linguists, academicians, curriculum designers, policymakers, administrators, researchers, and students.
Biocrust-forming cyanobacteria inoculation to restore degraded soils from dryland ecosystems
En las zonas áridas, la acción combinada del cambio climático y el aumento de la presión humana están causando una degradación acelerada de los ecosistemas. En este contexto, es necesario investigar nuevas estrategias de restauración que nos permitan mejorar las acciones de restauración en estas zonas. Para ello, en esta tesis se exploró el uso de biocostras, comunidades de organismos que colonizan los primeros centímetros del suelo y que viven en estrecha asociación con las partículas del suelo, para la recuperación de suelos degradados en ecosistemas áridos. De entre todos sus componentes, se investigó el potencial uso restaurador de la inoculación con especies de cianobact...
Doubled Haploidy in Model and Recalcitrant Species
Doubled haploids (DHs) are powerful tools to reduce the time and costs needed to produce pure lines to be used in breeding programs. DHs are also useful for genetic mapping of complex qualitative traits, to avoid transgenic hemizygotes, for studies of linkage and estimation of recombination fractions, for screening of recessive mutants. These are just some of the advantages that make DH technology one of the most exciting fields of present and future plant biotechnology. All of the DH methods have model species where these technologies have been developed, or that respond every efficiently to their corresponding induction treatment. However, not all the species of economical/agronomical inte...
Artisanal Small-Scale Gold Mining
This framework document provides a pragmatic approach for designing representative studies and developing uniform sampling guidelines to support estimates of morbidity that are explicitly linked to exposure to land-based contaminants from small-scale artisanal gold mining activities. A primary goal is to support environmental burden of disease evaluations, which attempt to attribute health outcomes to specific sources of pollution. The guidelines provide recommendations on the most appropriate and cost-effective sampling and analysis methods to ensure the collection of representative population-level data, sample size recommendations for each contaminant and environmental media, biological s...
