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Demyelinating diseases are characterized by an extensive loss of oligodendrocytes and myelin sheaths from axolemma, which commonly result in disability in young adults. To date, there is no effective treatment against these neurological disorders. In the adult brain, there are neural stem cells (NSCs) that reside within a niche denominated ventricular-subventricular zone (V-SVZ) in the lateral wall of the cerebral ventricles. NSCs give rise to neurons and oligodendrocytes that help preserve cellular homeostasis. Growing evidence indicates that V-SVZ progenitor cells may represent an endogenous source of oligodendrocytes that can be useful to treat demyelinating diseases. This e-Book “The v...
Providing an overview of Spanish and Portuguese cinema, this title contains 24 essays, each on a separate seminal film from the region, profiling work from the likes of Pedro Almodıvar and João Cesar Monteiro.
Examines Spain's contribution to international interest in Gothic culture, film and literatureWith the success of novels such as The Shadow of the Wind and films like The Others, contemporary Spanish culture has contributed a great deal to the imagery and experience of the Gothic, although such contributions are not always recognised as being specifically Spanish in origin. Contemporary Spanish Gothic is the first book to study how the Gothic mode intersects with cultural production in Spain today, considering some of the ways in which such production feeds off and simultaneously feeds into Gothic production more widely. Examining the works of writers and filmmakers like Carlos Ruiz ZafAn, Arturo PA(c)rez-Reverte, Pedro AlmodAvar and Alejandro AmenA!bar, as well as the further reaches of Spanish Gothic influence in the Twilight film series, the book considers images and themes like the mad surgeon and the vulnerable body, the role of the haunted house, and the heritage biopics of Francisco de Goya.
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Volumes 1 & 2 Guide to the MAJOR COMPANIES OF EUROPE 1991/92, Volume 1, arrangement of the book contains useful information on over 4000 of the top companies in the European Community, excluding the UK, over 1100 This book has been arranged in order to allow the reader to companies of which are covered in Volume 2. Volume 3 covers find any entry rapidly and accurately. over 1300 of the top companies within Western Europe but outside the European Community. Altogether the three Company entries are listed alphabetically within each country volumes of MAJOR COMPANIES OF EUROPE now provide in section; in addition three indexes are provided in Volumes 1 authoritative detail, vital information on ...
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During the sixteenth century, antiquarian studies (the study of the material past, comprising modern archaeology, epigraphy, and numismatics) rose in Europe in parallel to the technical development of the printing press. Some humanists continued to prefer the manuscript form to disseminate their findings – as numerous fair copies of sylloges and treatises attest –, but slowly the printed medium grew in popularity, with its obvious advantages but also its many challenges. As antiquarian printed works appeared, the relationship between manuscript and printed sources also became less linear: printed copies of earlier works were annotated to serve as a means of research, and printed works could be copied by hand – partially or even completely. This book explores how antiquarian literature (collections of inscriptions, treatises, letters...) developed throughout the sixteenth century, both in manuscript and in print; how both media interacted with each other, and how these printed antiquarian works were received, as attested by the manuscript annotations left by their early modern owners and readers.