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Osteoarthritis (OA) is one of the leading causes of disability in the nation. With an increase in the middle age and elderly population, arthritis-related disability is expected to dramatically increase in the coming years. The mechanically initiated progression of the disease may stem from alterations in joint kinetics, kinematics and muscular control. The purpose of this work was to examine multiple facets of human gait that may contribute to altered joint loading and in turn, the progression of arthritis. This was addressed through four studies. In order to discern how persons with knee OA can decrease contribution of the knee to support during walking, the first study analyzed the contri...