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Detection of Biological Agents for the Prevention of Bioterrorism
The threat of biological and chemical terrorism has driven the demand for timely techniques that can quickly detect the agent or agents used in an attack. The detection and/or prevention of these potential security threats provide significant scientific and technical challenges due to the combination of possible agents and modes of delivery available. This book will present a thorough look at the importance and technological challenges of mass spectrometry (MS) for the detection & identification of biological and chemical threats. This new contribution’s general aims are to draw the attention of recognized practitioners, experts and graduate students trying to grasp the latest MS developments in the cutting-edge fields of MS-biodefense technologies for the rapid/early/specific sensitive threat detection of pathogens, viruses, explosives, mycotoxins, chemical agents, and biological markers of xenobiotic chemicals.
Toxic Chemical and Biological Agents
This book critically assesses the current state of knowledge on new and important detection technologies, e.g. mass spectrometry, tandem mass spectrometry, biosensor detection and tissue imaging, in connection with toxic chemical and biological agents. In general, the main topics discussed concern the risks and consequences of chemical and biological agents for human health in general, with special emphasis on all biochemical and metabolic pathways including the reproductive system. The exposome, genetic risks and the environment, various health hazard agents, risk assessment, environmental assessment and preparedness, and analysis of sub-lethal effects at the molecular level are also discussed. In closing, the book provides comprehensive information on the diagnosis of exposure, and on health concerns related to toxic chemical and biological agents.
Fisheries Review
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Recent Advancements in the Diagnosis of Human Disease
Viruses, bacteria, fungi and parasites are known to cause the most common human disease. It frequently spreads through direct contact (from human to human, animal to human), and through contaminated food or water. With the advancement of diagnostic techniques, it is now possible to rapidly identify microorganisms causing human disease and correlate with the corresponding clinical infection. Therefore, there is a need to develop robust and high-throughput diagnostic methods to prevent and control human disease of public health importance. This book entitled “Recent Advancements in the Diagnosis of Human Disease” will help the scientific community to better understand the transmission dynamics of some human diseases.
Selected Topics in Mass Spectrometry in the Biomolecular Sciences
Many fundamental aspects of the methods used in mass spectrometry are here presented by outstanding scientists, with reference to very recent developments. The principles and applications of electrospray, ion spray and MALDI ionization technique are presented, together with optimised GC/MS interfacing systems and tools for quantitative analysis. A comprehensive treatment of modern instrumentation for mass analysis and detection is also included. The major part of the book deals with bioanalytical applications to peptides, proteins, oligonucleotides, polysaccharides, lipids and plant metabolites. Several papers are devoted to the evaluation of adduct formation between DNA and carcinogens. Env...
Detection of Chemical, Biological, Radiological and Nuclear Agents for the Prevention of Terrorism
This NATO-ASI installment is designed to provide an advanced overview for doctoral and post-doctoral candidates of the state-of-the-art technologies for bio-detection. The main objective of the work aims at providing readers with the latest developments necessary to successfully understand the CBRN Agents and their associated biotechnologies. The core methods focused on are mass spectrometry (including chromatographic and electrophoretic separation) and comparisons to spectroscopic, immunological and molecular analysis of chemical, biological and nuclear agents.
Carbohydrate Chemistry
In many fields, most notably medicine and molecular biology, the understanding of the structure and function of carbohydrates and glycoconjugates remains vital. This new volume contains critical reviews covering the latest findings in both chemical and biological sciences, and demonstrates the interdisciplinary nature of modern carbohydrate research. This book addresses diverse applications that continue to be major challenges for carbohydrate chemists. The book starts with a review of Gérard Descotes contribution to the field as a pioneer of French modern carbohydrate chemistry. Green nanocatalytic oxidation of free sugars, photosensitive glycomacrocycles, the application of disaccharides in supramolecular chemistry, recent advances in the radiation chemistry of polysaccharides, and the cell wall pectic rhamnogalacturonan II, an enigma in plant glycobiology are just some of the diverse topics presented in Volume 45. This set of reports will certainly benefit any researcher who wishes to learn about the latest developments in the carbohydrate field.
Produced Water
A state-of-the-art review of scientific knowledge on the environmental risk of ocean discharge of produced water and advances in mitigation technologies. In offshore oil and gas operations, produced water (the water produced with oil or gas from a well) accounts for the largest waste stream (in terms of volume discharged). Its discharge is continuous during oil and gas production and typically increases in volume over the lifetime of an offshore production platform. Produced water discharge as waste into the ocean has become an environmental concern because of its potential contaminant content. Environmental risk assessments of ocean discharge of produced water have yielded different results...
