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Cellular and Molecular Biology of Filamentous Fungi
An ideal starting point for any research study of filamentous fungi. • Incorporates the latest findings from such disciplines as physiology, taxonomy, genomics, molecular biology and cell biology. • Begins with an historical perspective, cell morphology and taxonomy, and moves on to such topics as cell growth, development, metabolism, and pathogenesis. • Presents the full range of the fungal kingdom and covers important topics as saprophytes, pathogens and endophytes. • Serves as a recommended text for graduate and undergraduate students.
Hospitality and Health
This title includes a number of Open Access chapters.In the last several decades, international traffic volume has significantly increased, raising the risk of infectious diseases and their spread. In this important volume, the impact of health issues is explored in connection with travel. Not only does the book explore the risk of diseases such as
Evolution of Fungi and Fungal-Like Organisms
Sequence analyses of numerous fungal genomes over the past two decades have provided us with extensive insights into the phylogenetic relationships of fungi and the distribution of genes and their inferred functions, across the fungal kingdom. It is now possible to answer questions about the origin of the fungal kingdom and fungal evolution with an analytical precision that was not possible before. This fully revised and updated 2nd edition of The Mycota, Vol. 14, addresses major aspects of fungal evolution. The book is divided into four sections covering the following main topics: • Evolutionary roots of fungi • Evolution of pathogenic strategies • Evolution of mutualistic interaction...
Genetics and Evolution of Infectious Diseases
Genetics and Evolution of Infectious Diseases is at the crossroads between two major scientific fields of the 21st century: evolutionary biology and infectious diseases. The genomic revolution has upset modern biology and has revolutionized our approach to ancient disciplines such as evolutionary studies. In particular, this revolution is profoundly changing our view on genetically driven human phenotypic diversity, and this is especially true in disease genetic susceptibility. Infectious diseases are indisputably the major challenge of medicine. When looking globally, they are the number one killer of humans and therefore the main selective pressure exerted on our species. Even in industria...
Protein Phosphatases
This book provides an up-to-date and comprehensive overview of protein phosphatase research, a rapidly evolving field with increasing importance in our understanding of the molecular basis of cell biology and of pathological processes. The book covers dephosphorylation processes involving serine/threonine, as well as tyrosine and histidine residues, and aims to be a useful resource for both the advanced reader as well as the newcomer to the field. It is also valuable for those working in the pharmaceutical and Biotech industries.
Drug Design
Right before the COVID-19 pandemic declared by the World Health Organization (WHO), life sciences have incited novel areas of studies that revolutionize the health sector. They are the studies of structural bioinformatics, pharmacogenomics, and metabolomics. The structural bioinformatics field is the very foundation of drug design research, as it provides insight into the molecular simulations and interactions between the biomolecules and the drug candidates. Secondly, pharmacogenomics is the starting point of any efforts in developing personalized medicine. Lastly, metabolomics provides instrumentation to elicit biomarkers for various diseases and health conditions. These studies have enabled current accelerated effort in COVID-19 research, as well as other communicable and non-communicable diseases.
Antifungal Drug Resistance
This detailed volume aims to elucidate the molecular mechanisms that underlie antifungal resistance. The book highlights methods to identify and characterize antifungal activity, to define and characterize strains with altered responses to antifungal drugs, to investigate the genetic and molecular mechanisms of these alterations of antifungal drug susceptibility, and, finally, to approach the study of these processes in animal models of fungal infection. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step and readily reproducible laboratory protocols, as well as tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Antifungal Drug Resistance: Methods and Protocols serves as an ideal resource for the field and a guide for investigators to study this important translational aspect of fungal biology.
Nutrient-Induced Responses in Eukaryotic Cells
Cells of all living organisms have the ability to respond to altered nutritional conditions. They have developed mechanisms to sense nutrient availability and to produce appropriate responses, which involve changes in gene expression and the production or degradation of certain enzymes and other proteins. In recent years, the understanding of nutrient-induced signal transduction has greatly advanced and the emerging picture is that nutrient signalling mechanisms evolved early in evolution. This book provides a detailed presentation and comparison of the key nutritional regulatory mechanisms in lower as well as higher eukaryotes, written by recognised experts in this expanding field.
Cell and Molecular Biology of Plastids
The present book provides a comprehensive overview of our current knowledge on plastid biogenesis, plastid-nuclear communication, and the regulation of plastid gene expression at all levels. It also assesses the state-of-the-art in key technologies, such as proteomics and chloroplast transformation. Written by recognized experts in the field, the book further covers crucial post-translational processes in plastid biogenesis and function, including protein processing.
