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Mitogen Activated Protein Kinases
Mitogen-activated protein kinase (MAPK) pathways are evolutionarily conserved in all eukaryotes and allow cells to respond to changes in the physical and chemical properties of the environment and to produce an appropriate response by altering many cellular functions. MAPKs are among the most intensively studied signal transduction systems. MAPK research is a very dynamic field in which new perspectives are continuously opening to the scientific community. Importantly, many MAPK inhibitors have been developed during the last years and are currently being tested in preclinical and clinical assays for inflammatory diseases and cancer treatment. In this research topic, we have gathered 14 paper...
The Tangled Tree
In this New York Times bestseller and longlist nominee for the National Book Award, “our greatest living chronicler of the natural world” (The New York Times), David Quammen explains how recent discoveries in molecular biology affect our understanding of evolution and life’s history. In the mid-1970s, scientists began using DNA sequences to reexamine the history of all life. Perhaps the most startling discovery to come out of this new field—the study of life’s diversity and relatedness at the molecular level—is horizontal gene transfer (HGT), or the movement of genes across species lines. It turns out that HGT has been widespread and important; we now know that roughly eight perc...
Current Sociology
Vols. 1-4 contain v. 1-4 of International bibliography of sociology.
17th International Conference on Soft Computing Models in Industrial and Environmental Applications (SOCO 2022)
This book contains accepted papers presented at SOCO 2022 conference held in the beautiful and historic city of Salamanca (Spain), in September 2022. Soft computing represents a collection or set of computational techniques in machine learning, computer science, and some engineering disciplines, which investigate, simulate, and analyze very complex issues and phenomena. After a thorough peer-review process, the 17th SOCO 2022 International Program Committee selected 64 papers which are published in these conference proceedings and represent an acceptance rate of 60%. In this relevant edition, a particular emphasis was put on the organization of special sessions. Seven special sessions were o...
La teología en España 1959-2009
El cristianismo histórico es decisión de razón, confesión de fe y praxis de vida. En los tres casos incluye la inteligencia que reclama sentido, la voluntad que demanda motivos y el corazón que necesita potencias sustentadoras para vivir. La teología es el órgano que en la Iglesia tiene como misión indagar las razones que abren la inteligencia a la fe a la vez que las razones que llevan la fe a la inteligencia; y ambas al amor y a la praxis. Una inteligencia que siempre es a la vez abertura trascendental al Misterio y atenimiento riguroso a la historia. Este libro es una meditación sobre la teología y la Iglesia en España, con la mirada puesta en Europa como trasfondo permanente, en la medida en que estas cuatro realidades están implicadas unas en otras y se han condicionado durante los últimos cincuenta años.
Diario oficial
None
Annual Reports in Medicinal Chemistry
Annual Reports in Medicinal Chemistry provides timely and critical reviews of important topics in medicinal chemistry with an emphasis on emerging topics in the biological sciences that are expected to provide the basis for entirely new future therapies. - Reviews on hot topics of interest in small molecule drug discovery heavily pursued by industrial research organizations - Provides preclinical information in the context of chemical structures - Knowledgeable section editors who evaluate invited reviews for scientific rigor
