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The importance of natural products and their metabolites in the treatment of pain and other diseases has been recognized by contemporary science, and a range of medications currently used in the clinic were indeed initially developed from natural products including medicinal plants. Historically, the mark of obtaining bioactive compounds with analgesic potential occurred in the 19th century when the first analgesic drugs obtained from medicinal plants were marketed. These included especially the opioids, such as morphine extracted from papaver (Papaver somniferum) and acetylsalicylic acid, which was synthesized from salicylic acid extracted from willow bark (Salix spp.). After almost two cen...
After a coup in 1964 that ousted Brazil’s leftist President João Goulart from power, a brutal military dictatorship took the reins of the state. As a result, elements of the persecuted Brazilian Communist Party split from a more peaceful, orthodox line and declared their intent to wage an insurgent war against the government, plunging the country into a conflagration of violence marked by cycles of urban bombings, political assassinations, institutional torture, kidnappings, and summary executions. Concrete Inferno relays this period in Brazil in a lucid narrative history, exploring what drove the military coup of 1964, the subsequent rise of the Armed Left, and the successes and failures of the insurgency and how it concluded. Stretching from the rumblings of discontent during João Goulart’s ascendancy in 1961 to the strange conclusion of the dictatorship in 1985, the book draws on new primary sources and a wealth of English- and Portuguese-language resources to provide a complete and evenhanded portrait of the conflict.
Heavily dominated by the sector of information and communication technologies, economic organizations pursue digital transformation as a differentiating factor and source of competitive advantage. Understanding the challenges of digital transformation is critical to managers to ensure business sustainability. However, there are some problems, such as architecture, security, and reliability, among others, that bring with them the need for studies and investments in this area to avoid significant financial losses. Digital transformation encompasses and challenges many areas, such as business models, organizational structures, human privacy, management, and more, creating a need to investigate ...
Episodic memory refers to the ability to remember personal experiences in terms of what happened and where and when it happened. Humans are also able to remember the specific perceptions, emotions and thoughts they had during a particular experience. This highly sophisticated and unique memory system is extremely sensitive to cerebral aging, neurodegenerative and neuropsychiatric diseases. The field of episodic memory research is a continuously expanding and fascinating area that unites a broad spectrum of scientists who represent a variety of research disciplines including neurobiology, medicine, psychology and philosophy. Nevertheless, important questions still remain to be addressed. This research topic on the Progress in Episodic Memory Research covers past and current directions in research dedicated to the neurobiology, neuropathology, development, measurement and treatment of episodic memory.
This timely book analyzes the governing experiences of the nine major pro-leftist governments in Latin America. The individual country case study chapters are preceded by chapters that frame the discussion by considering the theoretical implications of the Pink Tide experience relating to globalization, the state, and neo-extractivism. The contributors examine the Pink Tide policies and rhetoric that gained widespread approval and led to the long tenure of many of these governments. These included ambitious social programs, prioritizing the needs of the poor, nationalistic foreign policy, economic nationalism, and asserting control of strategic sectors of the economy. The book continues by t...
Trabalho da Enfermagem: esse é o tema deste livro que você tem em mãos. Aqui a Enfermagem é apresentada como um sujeito que se forma e se organiza politicamente no processo de trabalho. Pode-se dizer que não há novidade nessa apresentação. E isso é certo. Mas, também é certo que o imenso contingente de profissionais de Enfermagem precisa refletir muito sobre a sua própria profissão pela perspectiva do trabalho. Essa é uma afirmação que parece estar impregnada de tautologia. E pode ser. Ainda assim, insisto no convite para que todas as pessoas que exercem a profissão de Enfermagem separem ao menos um pequeno período de tempo para ler e refletir sobre as suas atividades pela perspectiva do trabalho, como a que é oferecida por este livro.
The vastness of knowledge in the world differs from the selection and organization of information, so that it can be used positively in society. Organizing relevant and pertinent information in the context of Gestational Diabetes Mellitus, correlating tothe relevant aspects in the academic context, becomes the objective of this book, since, as researchers, we believe that knowledge is universal. We have the mission of seeking this knowledge and bringing it to the collective as a way to promote the common good through science.In addition, we have as our central focus the search and understanding about Diabetes Mellitus, especially in its subdivision gestational,evaluating its characteristics ...