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At a time when 'textural' evidence is regarded as being 'obvious' ( . . . ) it becomes more and more difficult to find illustrations or even descriptions of the arrangements of the various constituents of 'traumatized' rocks. It is helpful in consequence to advise geology students that the study of thin sections is not only concerned with the identification of their mineral content. To do so would mean they could not see the wood for the trees. Accurate identification of the indi vidual minerals that form rocks is fundamental in their description but the analysis of their textures and habits is also essential. Study of textural features enforces constraints upon the inter pretation of the or...
Reprint of the original, first published in 1883.
"An excellent summary and interpretation of race relations in nineteenth-century California. Empirically rich and theoretically sophisticated, it is the last and best word on the historical origins of the racial hierarchy that contemporary multiculturalists are struggling to overcome."--George Fredrickson, Stanford University "Sometime soon in the 21st century, all of California's peoples will belong to minorities, and Almaguer's pathbreaking comparative history is indispensable for understanding how and why this society became so racially diverse. His study expands the borders of multicultural scholarship."--Ronald Takaki, University of California, Berkeley "Evocatively written and theoretically compelling, "Racial Fault Lines represents a benchmark in the writing of U.S. history. Almaguer blends sociological paradigms with rich historical narratives in his perspicacious examination of racial and class formation among nineteenth-century Californians. Me
"Mice have long been recognized as a valuable tool for investigating the genetic and physiological bases of human diseases such as diabetes, infectious disease, cancer, heart disease, and a wide array of neurological disorders. With the advent of transgenic and other genetic engineering technologies, the versatility and usefulness of the mouse as a model in biomedical research has soared. As a result, mouse colonies everywhere are expanding, and scientists who previously focused on other models are turning their attention to the mouse. Revised to reflect advances since the first edition, The Laboratory Mouse, Second Edition continues to be the most accessible reference on the biology and care of the laboratory mouse. This guide presents basic information and common procedures in detail to provide a quick reference source for investigators, technicians, and caretakers in the humane care and use of the mouse in the laboratory setting. Expanded, updated, and now in color, this new edition includes coverage of the biological features, husbandry, management, veterinary care, experimental methodology, and resources applying specifically to the mouse"--Provided by publisher.
This book reviews the role of exosomes and extracellular vesicles in both normal and pathological conditions. It first explains isolation methods for exosomes, and analyzes their fine structure and biological functions. Further, it highlights exosomes’ role as the key regulator in embryonic-maternal communication, and in the pathogenesis of various diseases, including cancer and urogenital, infectious, and neurodegenerative diseases. Moreover, it reviews the latest advances in using stem-cell-derived exosomes as a cell-free strategy in regenerative medicine, as well as the potential of exosomal microRNA as a promising non-invasive biomarker and targetable factor in cancer diagnosis and treatment. Lastly, it explores the use of natural and synthetic exosomes as nano-vehicles for efficient drug delivery.
This book summarizes several aspects of GD, which is caused by not well-understood multifactorial mechanisms. Common strategies seem to be key in the understanding of the syndrome, i.e., endothelial dysfunction and the role of other placenta cells such as trophoblasts. It is a book that will definitively help to increase the knowledge-based management of GD for the well being of the mother and the fetus. Several chapters lead us to the conclusion that pre-pregnancy and antenatal screening of women is required, something that will improve the management and outcome of a current pregnancy but will also optimize life-long health and well being considering the inter-generational consequences.
The Texas-Mexico border is trouble. Haphazardly splashing across the meandering Rio Grande into Mexico is--or at least can be--risky business, hazardous to one's health and well-being. Kirby W. Dendy, the Chief of Texas Rangers, corroborates the sobering reality: "As their predecessors for over one hundred forty years before them did, today's Texas Rangers continue to battle violence and transnational criminals along the Texas-Mexico border." In Riding Lucifer's Line, Bob Alexander, in his characteristic storytelling style, surveys the personal tragedies of twenty-five Texas Rangers who made the ultimate sacrifice as they scouted and enforced laws throughout borderland counties adjacent to t...
Proceedings of the Ophiolite Conference, held in Muscat, Oman, January 7-18, 1990