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Bulletin
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Cellular and Molecular Mechanisms Underlying the Pathogenesis of Hepatic Fibrosis
Worldwide, liver fibrosis is a major cause of morbidity and mortality and is associated with a high medical and economic burden. It is the common consequence of chronic liver injury due to various etiologies. During fibrogenesis, there is a progressive substitution of the liver parenchyma by scar tissue. Recent advances in the understanding of the history of liver fibrosis have shown that the pathogenesis is driven by different cell types and a large variety of soluble mediators. At present, scientists working in this field aim to increase basic knowledge, improve diagnostics, and try to translate experimental findings into new treatment modalities. This book includes 12 selected contributions from the Special Issue “Cellular and Molecular Mechanisms Underlying the Pathogenesis of Hepatic Fibrosis” that was published in Cells. These articles summarize current perspectives and findings in hepatic fibrosis research showing how scientists try to use basic scientific research to create new therapies and diagnostics.
Bulletin
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Information Bulletin
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Globular Clusters - Guides to Galaxies
The principal question of whether and how globular clusters can contribute to a better understanding of galaxy formation and evolution is perhaps the main driving force behind the overall endeavour of studying globular cluster systems. Naturally, this splits up into many individual problems. The objective of the Joint ESO-FONDAP Workshop on Globular Clusters - Guides to Galaxies was to bring together researchers, both observational and theoretical, to present and discuss the most recent results. Topics covered in these proceedings are: internal dynamics of globular clusters and interaction with host galaxies (tidal tails, evolution of cluster masses), accretion of globular clusters, detailed descriptions of nearby cluster systems, ultracompact dwarfs, formations of massive clusters in mergers and elsewhere, the ACS Virgo survey, galaxy formation and globular clusters, dynamics and kinematics of globular cluster systems and dark matter-related problems. With its wide coverage of the topic, this book constitutes a valuable reference of the scientific knowledge of the field.
Star Clusters (IAU S266)
Star clusters are important to many areas of astronomy, and as the basic building blocks of galaxies, they can be used as key diagnostic tools within a wide range of disciplines in astrophysics. Star cluster populations are powerful tracers of the formation, assembly and evolutionary history of their parent galaxies. Although their importance has been recognised for decades, only in recent years has this area seen a major investment in time and effort. IAU Symposium 266 consolidates the expertise of leading researchers from a variety of topical subfields in astrophysics, to provide a comprehensive presentation of cutting-edge developments in theory, observations and simulations of star clusters and star cluster systems across a range of sizes and epochs. This volume gives an account of this forefront research, answering fundamental questions that will improve our understanding of numerous related issues and show how this field will take its next major step forward.
Physics Briefs
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Deformation Characteristics of Geomaterials
This book is the international edition of the proceedings of IS-Seoul 2011, the Fifth International Symposium on Deformation Characteristics of Geomaterials, held in Seoul, South Korea, in September 2011.The book includes 7 invited lectures, as well as 158 technical papers selected from the 182 submitted. The symposium explored ideas about the complex load-deformation response in geomaterials, including laboratory methods for small and large strains; anisotropy and localization; time-dependent responses in soils; characteristics of treated, unsaturated, and natural geomaterials; applications in field methods; evaluation of field performance in geotechnical structures; and physical and numeri...
