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Neural Stem Cells
Over the last decade, neural stem cell research has provided penetrating insights into the plasticity and regenerative potential of the brain. Stem cells have been isolated from embryonic as well as adult central nervous system (CNS). Many non-CNS mammalian tissues also contain stem cells with a more limited repertoire: the replacement of tissue-specific cells throughout the li- time of the organism. Progress has been made in understanding fundamental stem cell properties that depend on the interplay of extrinsic signaling factors with intrinsic genetic programs within critical time frames. With this growing knowledge, scientists have been able to change a neural stem cell’s fate. - der ce...
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Textbook of Movement Disorders
Movement disorders in neurology concern involuntary movements of parts of the body. Many movement disorders are caused by nerve diseases such as Parkinson’s disease. Other causes include injuries, autoimmune diseases, infections and certain medicines. Many movement disorders are inherited so run in families (MedlinePlus). This book is a comprehensive guide to movement disorders for practising neurologists and trainees. Divided into 55 chapters, it discusses the basic science, clinical concepts, diagnosis and treatment of numerous conditions. Parkinson’s disease is covered in-depth and complete chapters are dedicated to movement disorders in children, MR imaging, and emergencies in movement disorders. Presented in an easy to read format, this manual includes 800 clinical photographs, illustrations and tables, as well as extensive references for each chapter. Key points Comprehensive guide to movement disorders for practising neurologists and trainees Parkinson’s disease covered in-depth Includes 800 images, illustrations and tables Extensive references for each chapter
Brody's Human Pharmacology - E-Book
Brody's Human Pharmacology is a well-established and much-loved textbook that guides students of medicine, pharmacology and other health professions through pharmacology from both basic and clinical perspectives. What can be a very difficult and complex topic is divided into easily digestible chapters, each of which is clearly structured from a therapeutic overview to mechanisms of action, relationships to clinical responses, pharmacokinetics, pharmacovigilance, new developments, and clinical relevance for all health professionals. - Contains all the essential aspects of pharmacology – suitable for exam preparation - Full color illustrations explain important processes and color-coded boxe...
Applications of Flow Cytometry in Stem Cell Research and Tissue Regeneration
A much-needed primer on the use of laser flow cytometry for stem cell analysis Laser flow cytometry is a powerful tool for rapid analysis of cells for marker expression, cell cycle position, proliferation, and apoptosis. However, no resources specifically address the use of this methodology for the study of stem cells; this is especially important as stem cell analysis involves specialized methods and staining procedures based on specific characteristics such as marker expression, cell size, drug transport, and efflux of the stem cells. Now, this book reviews these procedures, discusses the science behind them, and provides real-world examples to illustrate the usefulness of the methods. It ...
In Situ Detection of DNA Damage
Detection and analysis of DNA damage is of critical importance in a variety of biological disciplines studying apoptosis, cell cycle and cell di- sion, carcinogenesis, tumor growth, embryogenesis and aging, neu- degenerative and heart diseases, anticancer drug development, environmental and radiobiological research, and others. Individual cells within the same tissue or in cell culture may vary in the extent of their DNA damage and, consequently, can display different re- tions to it. These differences between individual cells in the same cell popu- tion are detected using in situ approaches. In situ is a Latin term meaning “on site” or “in place.” It is used to denote the processes ...
Encyclopedia of Mind Enhancing Foods, Drugs and Nutritional Substances, 2d ed.
This greatly expanded and revised edition contains more than 1,000 entries, covering everything from common everyday foods to the latest in genetic research--and beyond. Each substance's properties are objectively described based on the latest scientific evidence. Included are substances that not only claim to improve thinking and other brain functions, but those that are thought to help prevent brain damage and degeneration, prevent aging and extend the human lifespan, enhance social skills and moral behavior, induce altered states of consciousness, and improve mood, stamina, and energy.
Neural Stem Cells
Many questions related to stem cell properties and neural stem cell lineage and differentiation still linger. This second edition revises and expands upon the successful first edition in order to provide the most current, cutting-edge methods of today for the scientists working to answer these questions. The use of these step-by-step, readily reproducible laboratory protocols will allow investigators to produce pure populations that can serve as a means of understanding the biology of neural stem cells and adapting them for transplantation into disease models. This is an excellent source of information and inspiration.
Neurogenetics
The rapid identification and characterization of genes of neurological relevance holds great potential for offering insight into the diagnosis, management, and und- standing of the pathophysiologic mechanisms of neurological diseases. This volume in the Methods in Molecular BiologyTM series was conceived to highlight many of the contemporary methodological approaches utilized for the characterization of neu- logically relevant gene mutations and their protein products. Although an emphasis has been placed upon descriptions of methodologies with a defined clinical utility, it is hoped that Neurogenetics: Methods and Protocols will appeal not only to clinical laboratory diagnosticians, but als...
