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This book is dedicated to studying the thermodynamic bases of the structure-function relationship of proteins. It moves from the elementary principles of physical chemistry to the most current topics of biochemistry, including those that may be subject to some controversy. It considers thermodynamic properties related to the stability and function of proteins from the point of view of physics in a language that, without sacrificing conceptual rigor, is easy to read. Detailing the thermodynamics of protein-ligand interactions, protein naturation, allostery, oxidative phosphorylation and protein phosphorylation, the book will be of interest to students and teachers of chemistry, physics, biochemistry and biotechnology.
The great Spanish poet Juan Ramón Jiménez, winner of the Nobel Prize for Literature in 1956, was a mystic as will as a poet, and the deep spirituality which infuses so much of his writing makes itself felt with special fervor throughout this remarkable new collection of poems. Composed by Jiménez between the years 1917 to 1920, the works in this grouping vanished mysteriously, only to be rediscovered a half-century later among the author's private papers. Published in Spain for the first time in 1983, they appear now at last in a bilingual edition, the English lovingly rendered by the scholar and poet Antonio T. de Nicolás, and introduced by the Pulitzer Prize-winning poet Louis Simpson....
“An exquisite book, rich, shimmering, and truly incomparable.” —The New Yorker This lyric portrait of a boy’s companionship with his little donkey, Platero, is the masterpiece of Juan Ramón Jiménez, the Spanish poet awarded the 1956 Nobel Prize for Literature. Poetic, elegiac, it reveals the simple pleasures of life in a in a remote Andalusian village and is a classic work of literature, beloved by adults and children alike.
This book collates all the current knowledge of cardiac CT and presents it in a clinically relevant and practical textbook format appropriate for both cardiologists and radiologists. The images have been supplied by an experienced set of contributing authors and represent the full spectrum of cardiac CT. The field of Cardiovascular CT has experienced continued rapid evolution due to: 1) advances in technology, 2) expanded spectrum of cardiovascular applications and 3) significant growth in published data including large prospective multicenter studies. As increasing numbers have access to cardiac CT scanners, this book provides all the relevant information on this modality. This is an extensive update of the previous edition bringing the reader up-to-date with the immense amount of updated content in the discipline.
This extensively updated edition provides a comprehensive review of hypertrophic cardiomyopathy, the most common genetic disorder of the heart characterized by dysfunctional contractility at the sarcomere level. The disease produces abnormal and oftentimes focal hypertrophy on a macroscopic level that further impairs cardiac performance and may lead to life-threatening arrhythmias. This edition provides a practical approach, establishing evidence-based best practice for all scenarios. Hypertrophic Cardiomyopathy provides readers with key points and critical clinical pearls to assist them in managing patients. New chapters have been included on managing hypertension, sleep apnea, coronary art...
Written while in exile in the United States, Time and Space were originally intended to appear together in a single volume. Not until 1986, however, did they appear so in Spanish and not until 1988 were they published together in English. By presenting them together, Jiménez had wanted them to convey the same continuity of emotion, the same philosophical intensity, that he had experienced while writing them. All My Life, he wrote in his introduction, I have toyed with the idea of writing a continuous poem...with no concrete theme, sustained only by its own surprise, its rhythm, its discoveries, its light, its successive joys; that is, its intrinsic elements, its essence. That continuous poe...
Maps capture data expressing the economic complexity of countries from Albania to Zimbabwe, offering current economic measures and as well as a guide to achieving prosperity Why do some countries grow and others do not? The authors of The Atlas of Economic Complexity offer readers an explanation based on "Economic Complexity," a measure of a society's productive knowledge. Prosperous societies are those that have the knowledge to make a larger variety of more complex products. The Atlas of Economic Complexity attempts to measure the amount of productive knowledge countries hold and how they can move to accumulate more of it by making more complex products. Through the graphical representatio...