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Cancer Immunotherapies: From Efficacy to Resistance Mechanisms
Dr. Koguchi receives funding from Tesaro, a GSK company, Bristol-Myers Squibb, and Shimadzu Corporation.. Dr. Vujanovic is a co-inventor of a methodology licensed to INmune Bio, Inc. where a selective inhibitor of soluble TNF can be used to prevent or treat malignancies. Dr. Hansen is the recipient of a private grant from Eurostars Eureka. The other Topic Editors declare no competing interests.
Precision medicine approaches for heterogeneous conditions such as autism spectrum disorders (The need for a biomarker exploration phase in clinical trials - Phase 2m)
Many therapeutic interventions for autism spectrum disorder fail when they are examined in a clinical trial. Frequently, there is a subset of patients that responds very well to the intervention, while others do not, and the overall result does not yield a positive result. As autism spectrum disorder is highly heterogeneous in its underlying genetics and other etiological risk factors, as well as its heterogeneous phenotypic manifestation, this variability in response to any specific treatment is not entirely surprising. However, it remains a challenge to meaningfully subtype this heterogeneity for targeted treatment. The purpose of this research topic is to solicit articles that address the...
The Taoist Canon
Taoism remains the only major religion whose canonical texts have not been systematically arranged and made available for study. This long-awaited work, a milestone in Chinese studies, catalogs and describes all existing texts within the Taoist canon. The result will not only make the entire range of existing Taoist texts accessible to scholars of religion, it will open up a crucial resource in the study of the history of China. The vast literature of the Taoist canon, or Daozang, survives in a Ming Dynasty edition of some fifteen hundred different texts. Compiled under imperial auspices and completed in 1445—with a supplement added in 1607—many of the books in the Daozang concern the hi...
