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Cancer Immunotherapies: From Efficacy to Resistance Mechanisms
Dr. Koguchi receives funding from Tesaro, a GSK company, Bristol-Myers Squibb, and Shimadzu Corporation.. Dr. Vujanovic is a co-inventor of a methodology licensed to INmune Bio, Inc. where a selective inhibitor of soluble TNF can be used to prevent or treat malignancies. Dr. Hansen is the recipient of a private grant from Eurostars Eureka. The other Topic Editors declare no competing interests.
Precision medicine approaches for heterogeneous conditions such as autism spectrum disorders (The need for a biomarker exploration phase in clinical trials - Phase 2m)
Many therapeutic interventions for autism spectrum disorder fail when they are examined in a clinical trial. Frequently, there is a subset of patients that responds very well to the intervention, while others do not, and the overall result does not yield a positive result. As autism spectrum disorder is highly heterogeneous in its underlying genetics and other etiological risk factors, as well as its heterogeneous phenotypic manifestation, this variability in response to any specific treatment is not entirely surprising. However, it remains a challenge to meaningfully subtype this heterogeneity for targeted treatment. The purpose of this research topic is to solicit articles that address the...
The Taoist Canon
Taoism remains the only major religion whose canonical texts have not been systematically arranged and made available for study. This long-awaited work, a milestone in Chinese studies, catalogs and describes all existing texts within the Taoist canon. The result will not only make the entire range of existing Taoist texts accessible to scholars of religion, it will open up a crucial resource in the study of the history of China. The vast literature of the Taoist canon, or Daozang, survives in a Ming Dynasty edition of some fifteen hundred different texts. Compiled under imperial auspices and completed in 1445—with a supplement added in 1607—many of the books in the Daozang concern the hi...
The SAGE Handbook of Clinical Neuropsychology
Clinical Neuropsychology is a vast and varied field that focuses on the treatment, assessment and diagnosis of a range of cognitive disorders through a study and understanding of neuroanatomy and the relationship between the brain and human behavior. This handbook focuses on specific Neuropsychological disorders. It covers each of the classification systems involved before moving on to specific types of disorders from neurodevelopmental to neuropathological as well as brain injuries, trauma and neurodegenerative disorders. This handbook not only provides an in-depth overview of these Neuropsychological disorders, but also explores the history of the field as well its global challenges. The handbook is an essential tool for clinicians and scientists, as well as postgraduate students and researchers in a range of disciplines exploring the area. PART I BACKGROUND CONSIDERATIONS PART II NEURODEVELOPMENTAL DISORDERS PART III NEUROLOGICAL DISORDERS PART IV NEUROCOGNITIVE DISORDERS PART V TRAUMATIC BRAIN INJURY PART VI PSYCHIATRIC DISORDERS
