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This book provides latest findings in organotypic models in drug development and provides the scientific resonance needed in an emerging field of research in disciplines, such as molecular medicine, physiology, and pathophysiology. Today the research on human-based test systems has gained major interest and funding in the EU and the US has increased over the last years. Moreover, so-called 3R (reduce, replace, refine animal experiments) centres have been established worldwide.
Psychopathy is a very important concept for those working in the field of criminal justice - investigators, prosecutors, and those who have to evaluate, manage and treat offenders. In Psychopathy: Theory, Research and Implications for Society, detailed, empirically based contributions by the world's leading researchers describe the relevance of the construct to practical and policy issues, examining its relevance to such topics as treatment, risk management and recidivism. The use of the concept in a range of populations is discussed, including juveniles, children, and the mentally disordered, as well as across cultures. The major strength of the volume is that the validity of the psychopathy construct is enhanced by the extensive empirical support: contributors explore topics including the genetic, biological, affective, interpersonal and information processing models that underpin the disorder. Audience: All those dealing with offenders - psychologists, psychiatrists, lawyers, judges, prison administrators and those who formulate policy in the criminal justice system.
What makes curating feminist organizing? How do curators relate to contemporary feminist concerns in their local conditions and the globalized artworld? The book brings together twenty curatorial case studies from diverse regions of the globe. Reflecting their own curatorial projects or analyzing feminist-inspired exhibitions, the authors in this book elaborate feminist curating as that which is inspired to challenge gender politics not only within but also beyond the doors of the museum and gallery. Connecting their wider feminist politics to their curatorial practices, the book provides case studies of curatorial practice that address the legacies of racialized and ethnic violence, includi...
This book looks at a particular type of indigenous architecture that has developed in the city of Lhasa, the capital of Tibet. The focus is on the vernacular residential architecture in the form of the historic Lhasa Town House, as it was built and lived in from the mid-17th to mid-20th century. The book defines the Lhasa House as a distinct variety of traditional Tibetan architecture by providing a technical analysis and discussing the cultural framework and the development of a typology. (Series: HABITAT - INTERNATIONAL: Articles on International Urban Development / Schriften zur internationalen Stadtentwicklung - Vol. 18)
Bringing together texts and work by theorists and practitioners who are making material central to their work, this book reflects the diverse areas of inquiry which are expanding current material discourse. Focusing on the cultural, political, economic, technological and intellectual forces which shape material practices in architecture, the contributors draw on disciplines ranging from philosophy, history and pedagogy to art practice and digital and low-tech fabrication. By paying critical attention to material, a wide range of issues emerge which are otherwise excluded from architectural discourse, issues that shape and determine the buildings we make, the processes we use and the ways we understand them. Beautifully illustrated and designed, this book is a unique collection which will be of great interest to architectural practitioners and theorists who want to consider the wider implications of material practice, and to students who are developing their own approach to making buildings.
Das vorliegende Handbuch bietet eine umfassende Darstellung der Vielfalt der in der Schweiz bis in jüngste Zeit mündlich und schriftlich verwendeten Sprachen und Dialekte und der räumlichen und sozialen Bedingtheit ihres Auftretens. Es bezieht sich nicht ausschliesslich auf die Schweiz als viersprachiges Land, sondern geht neue Wege, indem es darüber hinaus das Englische sowie Sprachen berücksichtigt, deren heutige Präsenz in der Schweiz auf Migration beruht. Auch historische Sprachen und Dialekte, die in der Schweiz und im liechtensteinischen Sprachraum gesprochen werden, sowie die drei Schweizer Gebärdensprachen werden behandelt. Mit Ausblicken über die Schweiz hinaus bietet das Handbuch eine erweiterte Perspektive auf die Räume, die die Sprachen der Schweiz einnehmen. So wird das traditionelle Verständnis von Vielsprachigkeit um neue Aspekte und aktuelle Entwicklungen ergänzt.
This Gedenkschrift celebrates the memory of Professor Hans Sauer and his passion for travelling. The contributions in this volume explore different kinds of textual and temporal travels from various linguistic, literary, and philological perspectives.
Summarizing the current state of knowledge on the links between business and climate change, this timely Handbook analyzes how businesses contribute to and are affected by climate change, looking closely at their centrality in developing and deploying solutions to address this problem. Contributions from a global collection of scholars and practitioners explore a broad range of key industries’ impacts and responses to climate change, examining corporate strategy and leadership in the climate economy, functional perspectives and corporate practice, and climate finance.
This report calls for a better understanding of the effects of pharmaceutical residues in the environment, greater international collaboration and accountability distribution, and policy actions to prevent and remedy emerging concerns. Laboratory and field tests show traces of oral contraceptives causing the feminisation of fish and amphibians, and residues of psychiatric drugs altering fish behaviour. Antimicrobial resistance, linked to the overuse of antibiotics, has rapidly escalated into a global health crisis. Unless adequate measures are taken to manage the risks, pharmaceutical residues will increasingly be released into the environment as ageing populations, advances in healthcare, and intensification of meat and fish production spur the demand for pharmaceuticals worldwide. The report outlines a collective, life‑cycle approach to managing pharmaceuticals in the environment. A policy mix of source‑directed, use‑orientated and end‑of‑pipe measures, involving several policy sectors, can help to improve health and protect the environment.
This volume includes the proceedings of a workshop on Invariant Theory held at Queen's University (Ontario). The workshop was part of the theme year held under the auspices of the Centre de recherches mathematiques (CRM) in Montreal. The gathering brought together two communities of researchers: those working in characteristic 0 and those working in positive characteristic. The book contains three types of papers: survey articles providing introductions to computational invarianttheory, modular invariant theory of finite groups, and the invariant theory of Lie groups; expository works recounting recent research in these three areas and beyond; and open problems of current interest. The book is suitable for graduate students and researchers working in invarianttheory.