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Single-Domain Antibodies: Biology, Engineering and Emerging Applications
Single-domain antibodies (sdAbs) represent the minimal antigen binding-competent form of the immunoglobulin domain and have unique properties and applications. SdAbs are naturally produced as the variable domains of the heavy chain-only antibodies of camelid ruminants and cartilaginous fishes, but can also be engineered synthetically from autonomous human or mouse VH or VL domains. The scope of this research topic and associated e-book covers current understanding and new developments in (i) the biology, immunology and immunogenetics of sdAbs in camelids and cartilaginous fishes, (ii) strategies for sdAb discovery, (iii) protein engineering approaches to increase the solubility, stability and antigen-binding affinity of sdAbs and (iv) specialized applications of sdAbs in areas such diagnostics, imaging and therapeutics.
Large Meteorite Impacts and Planetary Evolution VI
"This volume contains a sizable suite of contributions dealing with regional impact records (Australia, Sweden), impact craters and impactites, early Archean impacts and geophysical characteristics of impact structures, shock metamorphic investigations, post-impact hydrothermalism, and structural geology and morphometry of impact structures - on Earth and Mars"--
Advances in Image and Video Technology
This book constitutes the refereed proceedings of the Third Pacific Rim Symposium on Image and Video Technology, PSIVT 2008, held in Tokyo, Japan, in January 2009. The 39 revised full papers and 57 posters were carefully reviewed and selected from 247 submissions. The symposium features 8 major themes including all aspects of image and video technology: image sensors and multimedia hardware; graphics and visualization; image and video analysis; recognition and retrieval; multi-view imaging and processing; computer vision applications; video communications and networking; and multimedia processing. The papers are organized in topical sections on faces and pedestrians; panoramic images; local image analysis; organization and grouping; multiview geometry; detection and tracking; computational photography and forgeries; coding and steganography; recognition and search; and reconstruction and visualization.
Wealth, Land and Property in Angola
Explores the history of land dispossession, slavery, colonialism, and inequality in Angola, from the sixteenth to the nineteenth century.
Encyclopedia of Organizational Knowledge, Administration, and Technology
For any organization to be successful, it must operate in such a manner that knowledge and information, human resources, and technology are continually taken into consideration and managed effectively. Business concepts are always present regardless of the field or industry – in education, government, healthcare, not-for-profit, engineering, hospitality/tourism, among others. Maintaining organizational awareness and a strategic frame of mind is critical to meeting goals, gaining competitive advantage, and ultimately ensuring sustainability. The Encyclopedia of Organizational Knowledge, Administration, and Technology is an inaugural five-volume publication that offers 193 completely new and...
Periphrasis and Inflexion in Diachrony
This volume brings together contributions from leading specialists in syntax and morphology to explore the complex relation between periphrasis and inflexion from both a synchronic and diachronic perspective. The chapters draw on data from across the Romance language family, including standard and regional varieties and dialects. The relation between periphrasis and inflexion raises questions for both syntax and morphology, and understanding the phenomena involved requires cooperation across these sub-domains. For example, the components that express many periphrases can be interrupted by other words in a way that is common in syntax but not in morphology, and in some contexts, a periphrasti...
20 years of independent cinema
Every January, from 1996 to 2016, while I was suffering with summer in Rio I received snowy news from the Sundance Festival through Carlos Brandão and his partner Myrna. In those 20 years, Carlos and Myrna were my main source of information about independent world cinema. It is a great joy to see all this material gathered in a book. Carlos was a passionate researcher and, along with Myrna, an experienced reporter. Their interviews and reports on films and directors that have passed through Sundance have the mark of someone who saw everything up close. And knew how to tell it. Carlos Alberto Mattos – Film Critic When Robert Redford founded the nonprofit Sundance Institute in 1981, the int...
Compendium report on multisectoral actions for the prevention and control of noncommunicable diseases and mental health conditions
Noncommunicable diseases (NCDs) and mental health conditions have a profound impact on societies, communities and individuals around the world. Their risk factors and determinants extend beyond the traditional health sector. Addressing this complex challenge necessitates interventions that reach beyond the boundaries of public health and requires a coherent, coordinated approach across all relevant governmental sectors. Understanding, documenting and sharing how governments implement multisectoral actions are essential to overcome these challenges and identify the capacity needs for coherent and sustainable responses to NCDs and mental health. In 2019, WHO Member States requested the Director-General to provide a consolidated report to the World Health Assembly analysing approaches to multisectoral action for NCD prevention and control, including addressing social, economic and environmental determinants of health. This compendium report is the Secretariat’s response to that request and features case studies from countries across WHO’s six regions.
