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The Proteomics Protocols Handbook
Hands-on researchers describe in step-by-step detail 73 proven laboratory methods and bioinformatics tools essential for analysis of the proteome. These cutting-edge techniques address such important tasks as sample preparation, 2D-PAGE, gel staining, mass spectrometry, and post-translational modification. There are also readily reproducible methods for protein expression profiling, identifying protein-protein interactions, and protein chip technology, as well as a range of newly developed methodologies for determining the structure and function of a protein. The bioinformatics tools include those for analyzing 2D-GEL patterns, protein modeling, and protein identification. All laboratory-based protocols follow the successful Methods in Molecular BiologyTM series format, each offering step-by-step laboratory instructions, an introduction outlining the principle behind the technique, lists of the necessary equipment and reagents, and tips on troubleshooting and avoiding known pitfalls.
Interdisciplinarity
In this volume, Julie Klein provides the first comprehensive study of the modern concept of interdisciplinarity, supplementing her discussion with the most complete bibliography yet compiled on the subject. In this volume, Julie Klein provides the first comprehensive study of the modern concept of interdisciplinarity, supplementing her discussion with the most complete bibliography yet compiled on the subject. Spanning the social sciences, natural sciences, humanities, and professions, her study is a synthesis of existing scholarship on interdisciplinary research, education and health care. Klein argues that any interdisciplinary activity embodies a complex network of historical, social, psychological, political, economic, philosophical, and intellectual factors. Whether the context is a short-ranged instrumentality or a long-range reconceptualization of the way we know and learn, the concept of interdisciplinarity is an important means of solving problems and answering questions that cannot be satisfactorily addressed using singular methods or approaches.
Evolutionary Biology
Since 1997, scientists of different disciplines sharing a deep interest in concepts and knowledge related to evolutionary biology have held the annual Evolutionary Biology Meetings in Marseille in order to discuss their research and promote collaboration. Lately scientists especially focusing on applications have also joined the group. This book starts with the report of the "12th Evolutionary Biology Meeting", which gives a general idea of the meeting’s epistemological stance. This is followed by 22 chapters, a selection of the most representative contributions, which are grouped under the following four themes: Part I Concepts and Knowledge - Part II Modelization - Part III Applied Evolutionary Biology - Part IV Applications in Other Fields -Part IV transcends the field of biology, presenting applications of evolutionary biology in economics and astronomy.
Sequence Alignment
The sequencing of the human genome involved thousands of scientists but used relatively few tools. Obtaining sequences is simpler, but aligning the sequences remains a complicated but underappreciated aspect of comparative molecular biology. This book discusses the practice of alignment, and the procedures by which alignments are established.
Crossing Boundaries
Boundary work studies examine how boundaries of knowledge are formed, maintained, broken down and reconfigured. This text investigates the claims, activities and institutional structures that define and legitimate interdisciplinary practices.
Membrane Trafficking
As membrane trafficking research has expanded over the past thirty years, a remarkable convergence of information has been gained by using genetic approaches in yeast cells with biochemical approaches in mammalian cells. This book reflects these advances by devoting one section of the book to yeast cells and the other to mammalian cells, with each section providing both classic and cutting-edge techniques to study macromolecular transport across the membranes.
Advances in Natural Computation
Annotation. This is volume I of the proceedings of the Second International Conference on Natural Computation, ICNC 2006. After a demanding review process 168 carefully revised full papers and 86 revised short papers were selected from 1915 submissions for presentation in two volumes. This first volume includes 130 papers related to artificial neural networks, natural neural systems and cognitive science, neural network applications, as well as evolutionary computation: theory and algorithms.
Human Resource Management
This introductory text aims to provide a balance between conceptual issues surrounding the debate on human-resource management and more practical aspects. This edition features an updated section on Europe and a number of new case studies.
Advanced Data Mining and Applications
This book constitutes the refereed proceedings of the First International Conference on Advanced Data Mining and Applications, ADMA 2005, held in Wuhan, China in July 2005. The conference was focused on sophisticated techniques and tools that can handle new fields of data mining, e.g. spatial data mining, biomedical data mining, and mining on high-speed and time-variant data streams; an expansion of data mining to new applications is also strived for. The 25 revised full papers and 75 revised short papers presented were carefully peer-reviewed and selected from over 600 submissions. The papers are organized in topical sections on association rules, classification, clustering, novel algorithms, text mining, multimedia mining, sequential data mining and time series mining, web mining, biomedical mining, advanced applications, security and privacy issues, spatial data mining, and streaming data mining.
Pattern Recognition
Pattern recognition continued to be one of the important research fields in computer science and electrical engineering. Lots of new applications are emerging, and hence pattern analysis and synthesis become significant subfields in pattern recognition. This book is an edited volume and has six chapters arranged into two sections, namely, pattern recognition analysis and pattern recognition applications. This book will be useful for graduate students, researchers, and practicing engineers working in the field of machine vision and computer science and engineering.
