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The Tumor Microenvironment
The fact that tumors are composed of both tumor cells and host cells has long been known. These tumor-associated cells include vascular endothelial cells and pe- cytes, as well as inflammatory cells such as neutrophils, monocytes, macrophages, mast cells and eosinophils, and lymphocytes. The tumor cells also interact with stromal cells and with elements of the tissue extracellular matrix. What has been less appreciated is the role that these cells could have in modulating the growth, invasion, and metastasis of the tumor. Early on, the elements of what we now call the tumor microenvironment were considered to be more or less innocent bysta- ers to the role of the tumor cells as they grew and...
The Geology of Spain
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The Military Intervenes
Explores the mechanisms of military intervention and its consequences. The contributors examine a succession of coups, attempted coups, and established military regimes, with a view to evaluate the role of the military as a ruling group and an organization fostering political development. These studies cast strong doubt on the abilities of the military as a modernizing and stabilizing agent, raising important questions about our policies on military assistance and arms sales. Bienen makes an especially strong plea for a reassessment of our military and economic-political policies in order to determine whether both are working toward the same goals.
House documents
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Tumor Dormancy and Recurrence
This volume will be the first to provide a comprehensive description of tumor dormancy. It will define the clinical and biological aspects of this phenomenon, as well as the cellular and molecular mechanisms associated with tumor dormancy. Chapters will be authored by world-renewed experts who are conducting cutting-edge research in the field. A unique feature will be a conclusive paragraph detailing future development and foreseeable clinical applications at the end of each chapter. The volume will serve as a fundamental instrument for every researcher and clinician interested in the field of tumor dormancy as well as a means of disseminating stimulating concepts and prompting the development of innovative technological solutions.
Building Knowledge Economies
In many parts of the world, knowledge is being put to work to accelerate and deepen the development process, promoting innovation and helping to generate wealth and jobs. This book discusses advanced development strategies that take into account education, information and communication technology, infrastructure, innovation, and the prerequisite economic and institutional regimes.
