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Liver and Environmental Xenobiotics
The general populations are incidentally exposed to a wide variety of xenobiotics as a consequence of the pollution of the environment by industrial and agricultural chemicals. Xenobiotics entering the animal will undergo one or more of the following fate: (a) elimination unchanged, (b) metabolism by enzymes, (c) spontaneous chemical transformation and (d) remain unchanged in the body. The actions of xenobiotics on the body exhibit certain specificity depending upon the compound's chemical structure and reactivity. Since the processes of metabolism change these chemical properties ofaxenobiotic, bewildering number of reactions continue to pose new challenges to toxicologists and pharmacologi...
Early Psychosis and Early Intervention: Clinical, Functional, and Cognitive Outcomes
Psychotic disorders are a group of severe mental disorders which affects 2-3% of the population and constitutes one of the leading causes of disability worldwide. Early intervention (EI) represents a major paradigm shift in psychiatric service and has been demonstrated to be effective in outcome improvement for first-episode psychosis (FEP) and at-risk mental state (ARMS). However, despite the promising findings, evidence has shown that a significant proportion of early psychosis patients still experience suboptimal clinical outcomes (such as high relapse risk, partial remission, early-onset treatment resistance, persistent negative symptoms, etc.), functional impairment and cognitive dysfun...
JJAP Letters
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National Library of Medicine Current Catalog
First multi-year cumulation covers six years: 1965-70.
JJAP
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