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In 1947 Leonard and Reva Brooks left for Mexico where Leonard planned to study painting for a year. In Mexico they discovered a vibrant, sometimes even dangerous, society and a dynamic artistic community, unlike the mundane world they had left behind in Canada with its stale and unwelcoming artistic scene. Invigorated by their new environment Leonard and Reva ended up staying for over half a century, playing a key role in establishing San Miguel de Allende as a world-famous art colony. In this new biography, John Virtue chronicles the lives of these two important artists and offers an intimate look at these complex and creative people. Virtue describes how they were caught up in the McCarthy...
This classical textbook has become indispensable for those in the front line dealing with metabolic disorders. The book is aimed at all those involved with this specialty including pediatricians, biochemists, dieticians, neurologists, internists, geneticists, psychologists, nurses, and social workers. This 4th edition has been thoroughly updated and revised. One new chapter on Neonatal screening by tandem MS/MS has been added and several new groups of disorders have been included. The book’s main feature is the strong emphasis on clinical presentation and treatment in acute and chronic situation.
John Virtue uncovers the dynamics of a prominent Ottawa family and reveals the divergent paths of brothers E.P. and Fred Taylor. E.P. became mid-century Canada's leading industrialist, while Fred became an artist and a Communist.
Each disease-related chapter begins with a detailed description of the patient and the delineating symptoms used for establishing the diagnosis and differential diagnosis. The highly detailed figures illustrate the metabolic derangement in a uniform way, together with essential aspects of the genetics involved, thus affording clarification and better understanding of the treatment. Topics covered range from general aspects such as the clinical approach, emergency treatment, diagnostic procedures, and psychosocial care for the child and the family, to specific discussions of new modes of treatment, including liver, bone marrow transplantation and somatic gene therapy.
With improved control of most environmental causes of disease, genetic illness has assumed a primary importance in the causation of handicap and mortality in all age groups. At present, effective therapy is available for relatively few genetic conditions and prenatal diagnosis is an important option for couples at high risk. The task of providing prenatal diagnosis for these couples requires a team approach between clinicians and scientists, and is complicated by the large number of diverse conditions and by the rapid developments in the field, both obstetric in relation to imaging and tissue sampling methods and genetic in relation to techniques for analysis. Against this background, the ai...
Reviewing and correlating in detail the synthetic, mechanistic, and physical properties ofenamines, this reference features an extensive discussion of all enamine literature ...numerous practical examples of synthetic enamine applications ... new information onoxidation-reduction reactions of enamines ... numerous tables and schemes that givefast, easy access to a wealth of useful data .. . and improved coordination among contributingauthors to reduce duplication and overlap.Thoroughly updating the original edition, Enamines, Second Edition contains over2,400 bibliographic citations that help researchers investigate particular subjects ingreat.er depth. It comprises an authoritative source for organic, synthetic, physical, andnatural products chemists in academe, industry, or government, as well as for advancedgraduate students in these disciplines.