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This comprehensive, interdisciplinary book covers different aspects of relevant human pathogens and commensals. The ongoing development of (meta-)genomic, transcriptomic, proteomic and bioinformatic analyses of pathogenic and commensal microorganisms and their host interaction provides a comprehensive introduction to the microbiological analysis of host-microbe interplay and its consequences for infection or commensalism.
Proceedings of the FEMS Symposium on Genes and Proteins Underlying Microbial Urinary Tract Virulence: Basic Aspects and Applications, held September 16-19, 1999, in Pécs, Hungary. Urinary tract infections are among the most frequent diseases caused by microbial pathogens. In this volume, researchers, clinical microbiologists and clinicians exchange the latest ideas covering four major aspects of this important topic: Genetic information, synthesis and assembly of virulence factors in urinary pathogens; Regulation of genes involved in the phenotypic appearance of virulence; Host-parasite interactions determining the process and outcome of the infection; Possible applications of the above aspects in diagnosis, therapy and prevention.
By presenting state-of-the-art results in logical reasoning and formal methods in the context of artificial intelligence and AI applications, this book commemorates the 60th birthday of Jörg H. Siekmann. The 30 revised reviewed papers are written by former and current students and colleagues of Jörg Siekmann; also included is an appraisal of the scientific career of Jörg Siekmann entitled "A Portrait of a Scientist: Logics, AI, and Politics." The papers are organized in four parts on logic and deduction, applications of logic, formal methods and security, and agents and planning.
This latest volume in the excellent Subcellular Biochemistry series is the first attempt to give an in-depth overview of the field of bacterial cell invasion. The current knowledge about all well-studied bacteria with the ability to invade eukaryotic cells is brought together, including bacteria pathogenic to humans and animals as well as the symbiotic rhizobia. Several chapters also deal with new approaches and applications regarding invasive bacteria. The book, which includes contributions from worldwide experts, discusses bacterial invasion ability within the context of bacteria-host cell interaction with the main focus on pathogenicity.
The normal function of the organism in various stages of activity can be seen as a process of mutual interaction of different regulation mechanisms building up the behaviour of the organism in changing situations and/or ages and/or levels of health or disease. Insights into these very complex relations which steer the action of the organism are particularly important for the study of internal medi cine. They can be seen as directly related to the understanding of pathological conditions. Recently, the medical community has focused its interest on the physiology and pathophysiology of events which happen during sleep. Although some information on pathological regulation during sleep was colle...