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Nanotechnologies and nanobiotechnologies will come to be the key technologies of the 21st century. The possibility to study, understand and control features of materials at the nanoscale promises developments in different areas ranging from material sciences to electronics and communication technologies or life sciences and medicine. If one wants to make good use of nanotechnological research and development one has to create an environment that meets the various ethical, legal and social challenges as well.
The incorporation of nanomaterials into products can improve performance, efficiency, and durability in various fields ranging from construction, energy management, catalysis, microelectronics, plastics, coatings, and paints to consumer articles such as foods and cosmetics. But innovation never comes at zero risk. The potential hazards resulting from human exposure during production, use, or disposal has raised concerns and targeted research early on. Safety of Nanomaterials along Their Lifecycle: Release, Exposure, and Human Hazards presents the state of the art in nanosafety research from a lifecycle perspective. Although major knowledge gaps still exist, solid data are now available to id...
This carefully selected balance of tutorial-like review chapters and advanced research covers hot topics in the field of biointerfaces, biosensing, nanoparticles at interfaces, and functionalized quantum dots. It also includes chapters arising from non-published work with topics such as surface design and their applications, as well as new developments in analytical tools for materials science and life science. Based on the very close and complementary collaboration of three distinguished leading research groups, this book highlights recent advances in the field ranging from synthesis and fabrication of organic and polymeric materials, surface and interface science to advanced analytical met...
This book introduces readers to interfacial reactions in confinement on stimuli-responsive homopolymer and diblock copolymer films. It also includes investigations concerning the immobilization of (bio)molecules and the fabrication of biomolecular patterns by reactive microcontact printing on these reactive polymer films. In turn, the book takes advantage of the microphase separation of diblock copolymer films to study the fabrication of nanopatterns, which could contribute to the future development of a model system that allows us to area-selectively deposit and address (bio)molecules. Given its scope, the book broadens readers’ perspective on the microfabrication of stimuli-responsive polymers.
An account of a three-year research program funded by the German government, in which physicists and physical chemists set off together with biologists and physicians to develop new techniques for medical and biological problems and ended up with sophisticated scientific solutions and innovative equipment, partly ready for the market. It not only includes a concise description of the new discoveries but also offers also an introduction to the various fields within optics.
Adverse Effects of Engineered Nanomaterials: Exposure, Toxicology, and Impact on Human Health, Second Edition, provides a systematic evaluation of representative engineered nanomaterials (ENM) of high volume production and their high economic importance. Each class of nanomaterials discussed includes information on what scientists, industry, regulatory agencies, and the general public need to know about nanosafety. Written by leading international experts in nanotoxicology and nanomedicine, this book gives a comprehensive view of the health impact of ENM, focusing on their potential adverse effects in exposed workers, consumers, and patients. All chapters have been updated with new sections ...
Of the 121,000 people on donor lists in the U.S., over 100,000 need kidney transplants and thousands die each year while waiting. Bioprinting aspires to build healthy kidney tissue from a patient's own cells and transplant this to boost failing kidneys without fear of rejection... As the 21st century dawned, a handful of inspired scientists tried to use 3D printing to create living human tissue. Their vision was to restore the health of people with intractable injuries, such as worn out cartilage, severed nerves, ailing kidneys, failing heartsthe gamut of human frailties. Their modest success energized others to join the quest. Now, after two decades of ingenious effort and hard work, they h...
This book presents the role of nanoparticles in cancer therapy, emphasizing their innovative applications across treatment, diagnosis and the development of therapeutic strategies. The first section of the book describes the applications of nanoparticles in cancer vaccines and gene therapy. It features discussions on polymeric nanoparticles as nanovaccine carriers, membrane-based nano-vaccines for immunotherapy and gene therapy techniques employing nanoparticles. The second section presents advanced nanomedicine approaches, specifying the role of chemodynamic nanoparticles in cancer theranostics, the application of low-dimensional nanomaterials and emerging strategies against drug resistance...
A detailed look at the latest research in non-invasive in vivo cytometry and its applications, with particular emphasis on novel biophotonic methods, disease diagnosis, and monitoring of disease treatment at single cell level in stationary and flow conditions. This book thus covers the spectrum ranging from fundamental interactions between light, cells, vascular tissue, and cell labeling particles, to strategies and opportunities for preclinical and clinical research. General topics include light scattering by cells, fast video microscopy, polarization, laser-scanning, fluorescence, Raman, multi-photon, photothermal, and photoacoustic methods for cellular diagnostics and monitoring of disease treatment in living organisms. Also presented are discussions of advanced methods and techniques of classical flow cytometry.