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First kisses are magic, just not always the good kind. Folk singer Nona May Taylor had it all until a jealous witch cursed her into old age after a kiss she barely remembers. Now she's traded her fame and fortune for a secluded cabin in the Montana wilderness. When she finds an injured hiker in her woods, she knows cute and charming Charlie is her last chance to find true love, the only thing that will break the curse. But Charlie has secrets, something is lurking in the woods around the cabin, and as Nona grows younger, the witch grows suspicious. Before winter's end, Nona will have to decide how hard she is willing to fight to win her life back, and how much she is willing to risk for true love.
On this deep space pleasure cruise, love is in the recycled air. Sunastara Jeka is passionate about two things: (1) meeting the needs of the varied species who holiday aboard her interstellar pleasure cruise during the day, and (2) avoiding attachments when the occasional guest meets her needs at night. Sunny's life is simple, straightforward, and safe until a former one-night stand becomes her newest crew member. Freddie has never forgotten that night with Sunny. He's ecstatic to see her again, until she tells him she never dates her coworkers. Determined not to lose this confident, sexy, hysterical woman again, Freddie bides his time, pursuing a purely professional relationship with Sunny ...
To compile this up-to-date handbook, Dr. Charles Snow of the University of Kentucky Medical Center has assembled works by a premier group of active investigators who meet the needs of todays researchers. The handbookprovides a broad overview of the historical and current research in B- and T-cell biology, and presents the latest developments in this fast-breaking field to all professionals concerned with the humoral immune response of the body.
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Natural Autoantibodies provides an in-depth analysis of all aspects of natural antibodies. The book examines the advantages and pitfalls of every type of technique that is widely used for detecting autoantibodies. It also covers the sequencing of human autoantibody genes, discussing how sequencing is undertaken and the genetic clues available to elucidate the genetic origins of autoimmunity. Animal models of autoimmunity are also covered, and the up-to-date account provided in this book explains how natural autoantibodies have important regulatory functions and also occasionally serve as templates for autoimmunity. Other topics examined in Natural Autoantibodies: Their Physiological Role and Regulatory Significance include idiotypes of natural autoantibodies; the pathogenic role of natural autoantibodies; and methods to measure the effects of genetic and sex hormones, as well as aging, on natural autoantibodies. The book will be an excellent research tool and reference for immunologists, rheumatologists, and others interested in the topic.
A million stars, two hearts, only one cave. Half-human Elani's life aboard the interstellar pleasure cruise, the Ignisar, is changed forever when she installs her LunaCorp hormone upgrade. Seeking answers, she's thrown into the path of the ship's handsome but curt physician, Sem, an empath from the ocean planet Portis. When a mysterious voice hacks Elanie's programming and forces her to jump through space, Sem follows her to the edges of the Known Universe. Stranded on an uncharted planet, they become unlikely allies fighting to survive deadly blizzards, arctic ice caves, and a mysterious hedonistic community, all while navigating their unexpected and tumultuous feelings for each other. Set against the backdrop of a deep space pleasure cruise through a neighboring solar system, this steamy, emotional, heart-pounding series is perfect for fans of Honey Phillips and Ruby Dixon.
This volume illustrates the functional properties of NAbs. Authors from pioneering groups report in their chapters on the tissue homeostatic, tissue regenerating and regulatory properties of NAbs and NAbs in pooled human IgG. Scientists interested in the regulation and modulation of components of the immune system found a whole variety of NAbs to cytokines with regulatory and protective functions and NAbs that modulate, e.g., dendritic cells, regulatory T cells, B cells and granulocytes. Considering the large plasma pools and initial difficulties in preparing IVIG that does not induce adverse effects upon infusion into recipients, this volume ends with a historical chapter on how pooled human plasma was fractionated and the IgG component pretreated for a safe intravenous application.
This authoritative handbook covers all aspects of immunosenescence, with contributions from experts in the research and clinical areas. It examines methods and models for studying immunosenescence; genetics; mechanisms including receptors and signal transduction; clinical relevance in disease states including infections, autoimmunity, cancer, metabolic syndrome, neurodegenerative diseases, frailty and osteoporosis; and much more.
KEY TOPICS: Ig A Deficiency The Role of Cellular Immunity in Protection against HIV Infection Mouse Mammary Tumour Virus: Immunological Interplays between Virus and Host The Transporter Associated with Antigen Processing NF-kB in cytokine gene expression NF-kB as a target for immunosuppressive and anti-inflammatory molecules Key Features* A Deficiency* The Role of Cellular Immunity in Protection against HIV Infection* Mouse Mammary Tumor Virus: Immunological Interplays between Virus and Host* The Transporter Associated with Antigen Processing* NF-kB in cytokine gene expression* NF-kB as a target for immunosuppressive and anti-inflammatory molecules
Advances in Immunology