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Transient Receptor Potential Channels offers a unique blend of thoughtfully selected topics ranging from the structural biology of this fascinating group of ion channels to their emerging roles in human diseases. This single book covers TRP channels of yeasts, flies, fishes frogs and humans. And from the biophysics of primary thermo-sensory events in cells to the thermosensation at whole organism level, from physiology of pain to the development of pain-killers, from psychiatric illnesses to cancers, from skin cells to sperms, from taste buds to testes, from established facts to heated debates, this book contains something for every TRP enthusiasts, beginner and expert alike. It includes crucial background information, critical analysis of cutting edge research, and ideas and thoughts for numerous testable hypotheses. It also shows directions for future research in this highly dynamic field. It is a book readers will be just as eager to give to others as keep for themselves.
Calcium ions represent Mother Nature’s ‘ion-of-choice’ for regulating fundamental physiological functions, as they initiate a new life at the time of fertilization and guide subsequent developmental and physiological functions of the human body. Calcium channels, which act as gated pathways for the movement of calcium ions across the membranes, play a central part in the initiation of calcium signals, and defects in calcium channel function have been found to result in a plethora of human diseases, referred to as the calcium channelopathies. Pathologies of Calcium Channels brings together leading international experts to discuss our current understanding of human diseases associated with the various calcium channels, from their molecular basis to potential future therapeutic targeting of calcium channels.
"This is the urban century in which, for the first time, the majority of people live in towns and cities. Understanding how people influence, and are influenced by, the 'green' component of these environments is therefore of enormous significance. Providing an overview of the essentials of urban ecology, the book begins by covering the vital background concepts of the urbanisation process and the effect that it can have on ecosystem functions and services. Later sections are devoted to examining how species respond to urbanisation, the many facets of human-ecology interactions, and the issues surrounding urban planning and the provision of urban green spaces. Drawing on examples from urban settlements around the world, it highlights the progress to date in this burgeoning field, as well as the challenges that lie ahead"--Provided by publisher.
This book presents a complete overview of COVID-19 and provides a series of in-depth analyses of the literature and a comprehensive discussion and perspectives on promising anti-SARS-CoV-2 agents based on the system of ethnopharmacology, which covers Chinese medicine, traditional medicines of India and Africa, Turkish folk medicine, essential oils, and some well-known medicinal plants. In this book, the current status of therapeutic strategies against COVID-19 was summarized and a perspective of potential options for the future was proposed. Based on ethnopharmacology, some well-established traditional herbal formulations and bioactive compounds with anti-virus activity were repurposed for m...
The severity of interconnected socio-economic and environmental impacts on landscapes and people across Africa are exacerbated as a result of land degradation, conflict, poor governance, competition for land and inequality, and exacerbated by climate change. In pursuing pathways towards a more resilient future, collaborative and multi-stakeholder governance and management of landscapes have been promoted by government agencies, NGOs and conservation organisations as a possible solution. However, there is no single way to achieve effective collaboration, and different landscape projects have experimented with different entry points and engagement processes. Grounded in partnerships amongst researchers, practitioners and development partners with expertise in landscape governance and management in Africa, this book describes and collates key lessons from practice for supporting more resilient and equitable landscapes.
This volume discusses the effects of indoor air environment and pollution in modern buildings on human health. Highlighting epidemiological studies and the determining factors, it offers proposals for improving indoor air quality (IAQ) in different environments. Focusing not only on homes and offices, but also vehicles and aircrafts, it details practical methods of measuring and assessing indoor air quality. Written by pioneering researchers, Indoor Environmental Quality and Health Risk toward Healthier Environment for All is a valuable resource for both new and established researchers as well as students seeking a comprehensive overview of the facts on indoor air quality and health. Also is also of interest to hygiene experts in industry, occupational health and safety professionals, governmental public health sectors and school physicians.
Edited by two renowned specialists in CSR in the Middle East, this book features contributions from leading CSR scholars in the region. Each chapter provides a comprehensive and up-to-date discussion of the most pertinent issues within the subject area, and also includes a number of real life case studies addressing emerging and timely CSR topics facing organizations in the Middle East. The book is intended for researchers and students of CSR, providing a state-of-the-art overview of the key themes, best practices and current debates focused upon the Middle East.
Advances in molecular biology and biotechnology are increasing at a rapid pace, both in the development of new methodologies and in their practical applications. This popular textbook has been revised and updated to provide an overview of this exciting area of bioscience and to reflect a number of the key developments driving this expansion. Chapters on the basic methods of key technologies such as nucleic acid analysis and bioinformatics are presented, in addition to genomics and proteomics, which highlight the impact of molecular biology and biotechnology. New chapters on important and emerging methods have been introduced such as gene editing, next generation sequencing, nanobiotechnology...
This handbook defines the contours of environmental sociology and invites readers to push boundaries in their exploration of this important subdiscipline. It offers a comprehensive overview of the evolution of environmental sociology and its role in this era of intensified national and global environmental crises. Its timely frameworks and high-impact chapters will assist in navigating this moment of great environmental inequality and uncertainty. The handbook brings together an outstanding group of scholars who have helped redefine the scope of environmental sociology and expand its reach and impact. Their contributions speak to key themes of the subdiscipline—inequality, justice, populat...