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Gerald Reaven, the discoverer of Syndrome X, and a panel of world-class investigators thoughtfully summarize our current understanding of how insulin resistance and its compensating hyperinsulinemia play a major role in the pathogenesis and clinical course of high blood pressure and cardiovascular disease-the so-called diseases of Western civilization. These distinguished authorities detail, for the first time, the pathophysiological consequences and the clinical syndromes, excluding Type 2 diabetes, related to insulin resistance. They also examine the genetic and lifestyle factors that contribute to the wide differences in insulin action that exist in the population at large. Timely and authoritative, Insulin Resistance: The Metabolic Syndrome X illuminates the full importance of insulin resistance as a major cause of hypertension, heart disease, and polycystic ovary syndrome.
Approximately fifty articles that were published in The Mathematical Intelligencer during its first eighteen years. The selection demonstrates the wide variety of attractive articles that have appeared over the years, ranging from general interest articles of a historical nature to lucid expositions of important current discoveries. Each article is introduced by the editors. "...The Mathematical Intelligencer publishes stylish, well-illustrated articles, rich in ideas and usually short on proofs. ...Many, but not all articles fall within the reach of the advanced undergraduate mathematics major. ... This book makes a nice addition to any undergraduate mathematics collection that does not already sport back issues of The Mathematical Intelligencer." D.V. Feldman, University of New Hamphire, CHOICE Reviews, June 2001.
A research team claim their new product will boost the performance of every athlete in the world. The claims cause alarm, and the Lambeth Group send Gavin Shawlens to investigate. The product is stolen, top athletes disappear, and the research team are unaware that their product arose from the ashes of evil Second World War research. Gavin must stop the product launch before more people die horribly. When Gavin disappears, Zoe Tampsin, his associate from the Lambeth Group, must find him before he becomes the next victim to die. As if Zoe doesn’t have enough on her plate. Past events in Gavin’s life catch up with him. A powerful US general has decided that Gavin Shawlens must die to prevent exposure of a 60-year-old secret capable of world-changing and power-shifting events.
Measures of biological variation have long been associated with many indices of social inequality. Data on health, nutrition, fertility, mortality, physical fitness, intellectual performance and a range of heritable biological markers show the ubiquity of such patterns across time, space and population. This volume reviews the current evidence for the strength of such linkages and the biological and social mechanisms that underlie them. A major theme is the relationship between the proximate determinants of these linkages and their longer-term significance for biologically selective social mobility. This book therefore addresses the question of how social stratification mediates processes of natural selection in human groups. Data like this pose difficult and sensitive issues for health policy and developments in this area and in eugenics are reviewed for industrialised and developing countries.
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