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Methods in Cell Biology
Methods in Cell Biology
A Life Course Approach to Mental Disorders
A Life Course Approach to Mental Disorders examines the causes and consequences of a wide-range of mental disorders throughout life, from the peri-natal period through old age.
The Wiley Handbook of Anxiety Disorders
This state-of-the-art Handbook on the research and treatment of anxiety and related disorders is the most internationally and clinically oriented Handbook currently available, encompassing a broad network of researchers, from leading experts in the field to rising stars. The very first handbook to cover anxiety disorders according to the new DSM-5 criteria Published in two volumes, the International Handbook provides the most wide-ranging treatment of the state-of-the-art research in the anxiety disorders Offers a truly international aspect, including authors from different continents and covering issues of relevance to non-Western countries Includes discussion of the latest treatments, including work on persistence of compulsions, virtual reality exposure therapy, cognitive bias modification, cognitive enhancers, and imagery rescripting Covers treatment failures, transdiagnostic approaches, and includes treatment issues for children as well as the older population Edited by leaders in the field, responsible for some of the most important advances in our understanding and treatment of anxiety disorders 2 Volumes
Targeted Therapies in Cancer
From its introduction, oncological chemotherapy has been encumbered by poor selectivity because antiproliferative drugs are often toxic not only to tumor cells but also to important populations of the body’s non-neoplastic cells. Modern targeted therapies interact with defined molecules present on cancer cells, adding increased selectivity to their toxic effects. This book presents an integrated critical view on the theories, mechanisms, problems and pitfalls of the targeted therapy approach.
Molecular Staging of Cancer
An explosion of information has occurred since scientists began to define the molecular events that describe the malignant transformation and progression of cells and their development towards a life-threatening metastatic disease. The First International Congress on Molecular Staging of Cancer, held in Munich in December 2001, aimed to establish an international platform of exchange among molecular biologists, cell biologists, tumor immunologists, and clinical and surgical oncologists. This network approach should be fruitful for both clinicians and researchers. The highlighted topics included tumor-associated proteolysis, minimal residual disease, new approaches for molecular diagnosis and targeting, and the first molecular staging models. One session focused on technology transfer, opening up a new field of funding for innovative concepts. Finally, the impact of molecular staging on clinical strategies was discussed.
Superficial Esophageal Neoplasm
This book, containing the proceedings of the 2000 Kyoto Symposium on Esophageal Cancer, is an important contribution for all types of physicians interested in both squamous and adenocarcinoma of the esophagus. The volume has great legitimacy and relevance. The symposia hosted by Professor Masayuki Imamura brought together the leaders in several disciplines from Japan with other acknowledged authorities from Europe, the United States, Australia, and other parts of Asia. Japan has long been a leader in making advances in understanding the pathology, diagnosis, and treatment of esophageal squamous cell carcinoma, for several decades originally led by Professor Komei Nakayama and his students. I...
Bone Marrow Lymphoid Infiltrates
This monograph aims to cover in depth all aspects of bone marrow lymphoid infiltrates, in the context of their wide spectrum of benign, borderline and malignant expressions. As the bone marrow is no longer considered a selective diagnostic procedure in the field of haematopathology and haematology,but a routine need to other subspecialists, we intend to provide a comprehensive treatise for beginners and experienced practitioners alike who deal with patients that are investigated or treated for lymphomas and lymphoid leukemias, manifest with laboratory or clinical signs suspicious for haematological diseases or show features mimicking haematological conditions.
Principles of Behavioral Neuroscience
A user-friendly introduction to brain and behavior, highlighting essential concepts with studies employing modern neuroscience techniques.
Age of Onset of Mental Disorders
This book presents a thorough and critical review of current knowledge about the age of onset of mental disorders. The opening chapters offer information about the impact of the age of onset on the clinical picture, course, and outcome of physical illnesses, and about the neurobiological implications and correlates of different ages of onset. The impact and correlates of the ages of onset of all the most important mental disorders are then discussed in detail by internationally renowned scientists. The background to the book is the recognition that a better understanding of age of onset makes it possible to estimate the lifetime risk of disorders, helps to elucidate pathogenesis, and facilitates efficient, targeted clinical management. The book will be of value for clinicians, mental health professionals, mental health researchers, epidemiologists, and different stakeholders in the mental health field.
Mohs Micrographic Surgery
Mohs Micrographic Surgery, an advanced treatment procedure for skin cancer, offers the highest potential for recovery--even if the skin cancer has been previously treated. This procedure is a state-of-the-art treatment in which the physician serves as surgeon, pathologist, and reconstructive surgeon. It relies on the accuracy of a microscope to trace and ensure removal of skin cancer down to its roots. This procedure allows dermatologists trained in Mohs Surgery to see beyond the visible disease and to precisely identify and remove the entire tumor, leaving healthy tissue unharmed. This procedure is most often used in treating two of the most common forms of skin cancer: basal cell carcinoma and squamous cell carcinoma. The cure rate for Mohs Micrographic Surgery is the highest of all treatments for skin cancer--up to 99 percent even if other forms of treatment have failed. This procedure, the most exact and precise method of tumor removal, minimizes the chance of regrowth and lessens the potential for scarring or disfigurement
