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Nowadays, chirality is widely accepted as an important factor in molecular recognition processes and the biological activity of many pharmaceutical drugs and agrochemicals; this is confirmed by the continuous need for synthetic methods which lead to single or enriched enantiomers of such compounds. By presenting a review of the various and more recently developed approaches for both metal-transition and organocatalysis, this volume describes the development of “greener” asymmetric reactions which preserve stereoselectivity. The author summarizes the impressive amount of research that has been gathered within this field into three chapters focusing on: i)the search of alternative catalysts, ii) alternative solvents, and iii) alternative synthetic strategies and processes. For each topic, the fundamentals and some valuable applications are discussed.
In 1918 Lord Leverhulme bought the island of Lewis with ambitious plans to massively expand its fishing industry and increase its population. In 1923, when his plans had failed, he offered it free of charge to the islanders in two parts. One part, which included impoverished rural areas, was economically unviable. But the other, based around the busy fishing port and administrative centre of Stornoway, was a different matter. In accepting Leverhulme's offer, the hardheaded, churchgoing business class of Stornoway took on the responsibility of making the radical slogan 'Land for the People' a reality. It was an unlikely coupling, but it worked to perfection. The 20th century was a tumultuous ...
Vols. for 1898-1968 include a directory of publishers.
Photosynthesis is a process on which virtually all life on Earth depends. To answer the basic questions at all levels of complexity, from molecules to ecosystems, and to establish correlations and interactions between these levels, photosynthesis research - perhaps more than any other discipline in biology - requires a multidisciplinary approach. Congresses probably provide the only forums where progress throughout the whole field can be overviewed. The Congress proceedings give faithful pictures of recent advances in photosynthesis research and outline trends and perspectives in all areas, ranging from molecular events to aspects of photosynthesis on the global scale. The Proceedings Book, a set of 4 (or 5) volumes, is traditionally highly recognized and intensely quoted in the literature, and is found on the shelves of most senior scientists in the field and in all major libraries.
Finance is a notoriously difficult core subject for business undergraduates, which many find difficult to understand. The area has been dominated by large and complex introductory texts - often from the US - which many lecturers find too detailed and unwieldy. This carefully developed and researched text will fill this gap by providing a succinct, modular, UK-focused introduction to the subject of financial management. Quality controlled by an academic review panel, the content and approach has been rigorously developed to answer the needs of non-finance students. The user-friendly features and design will be of great appeal to the many undergraduates who find finance a difficult subject. Examples, models, formulas, and exercises are lucidly and clearly presented, supported by strong pedagogical features - learning objectives, worked examples, key learning points, further reading, practical assignments, references, case studies and teacher's guide. This ensures that Financial Management will prove the most accessible text for business and finance students.
Although many books exist on the subject of chiral chemistry, they only briefly cover chiral synthesis and analysis as a minor part of a larger work, to date there are none that pull together the background information and latest advances in one comprehensive reference work. Comprehensive Chirality provides a complete overview of the field, and includes chiral research relevant to synthesis, analytic chemistry, catalysis, and pharmaceuticals. The individual chapters in each of the 9 volumes provide an in depth review and collection of references on definition, technology, applications and a guide/links to the related literature. Whether in an Academic or Corporate setting, these chapters wil...
The world is chiral. Most of the molecules in it are chiral, and asymmetric synthesis is an important means by which enantiopure chiral molecules may be obtained for study and sale. The aim of this book is to present a detailed analysis of the factors that govern stereoselectivity in organic reactions.
Filling the gap for a systematic, authoritative, and up-to-date review of this cutting-edge technique, this book covers both low and high frequency EPR, emphasizing the importance of adopting the multifrequency approach to study paramagnetic systems in full detail by using the EPR method. In so doing, it discusses not only the underlying theory and applications, but also all recent advances -- with a final section devoted to future perspectives.
This concise text takes a symptom-based approach to evaluate and treat sleep disorders. Divided into two sections, this book emphasizes practical information in the patient history and physical, the latest screening techniques and common sleep disorders that either cause sleepiness, insomnia, or restless sleep. Chapters cover the epidemiology, pathophysiology, diagnosis and treatment of major sleep disorders and incorporate new classification systems from the International Classifications of Sleep Disorders, 3rd Edition and the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5). Sleepy or Sleepless provides a solid foundation to clinicians who want to better evaluate patients with sleep-related complaints.
Organocatalyzed Reactions I and II presents a timely summary of organocatalysed reactions including: a) Enantioselective C-C bond formation processes e.g. Michael-addition, Mannich-reaction, Hydrocyanation (Strecker-reaction), aldol reaction, allylation, cycloadditions, aza-Diels-Alder reactions, benzoin condensation, Stetter reaction, conjugative Umpolung, asymmetric Friedel-Crafts reactions; b) Asymmetric enantioselective reduction processes e.g. Reductive amination of aldehydes or ketones, asymmetric transfer hydrogenation; c) Asymmetric enantioselective oxidation processes; d) Asymmetric epoxidation, Bayer-Villiger oxidation; e) Enantioselective a-functionalization; f) A-alkylation of ketones, a-halogenation and a-oxidation of carbonyl compounds.