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Chemoinformatics is paramount to current drug discovery. Structure- and ligand-based drug design strategies have been used to uncover hidden patterns in large amounts of data, and to disclose the molecular aspects underlying ligand-receptor interactions. This Research Topic aims to share with a broad audience the most recent trends in the use of chemoinformatics in drug design. To that end, experts in all areas of drug discovery have made their knowledge available through a series of articles that report state-of-the-art approaches. Readers are provided with outstanding contributions focusing on a wide variety of topics which will be of great value to those interested in the many different and exciting facets of drug design.
This book is the first comprehensive collection of electronic aspects of different kinds of elastomer composites, including combinations of synthetic, natural and thermoplastic elastomers with different conducting fillers like metal nanoparticles, carbon nanotubes, or graphenes, and many more. It covers elastomer composites, which are useful in electronic applications, including chemical and physical as well as material science aspects. The presented elastomer composites have great potential for solving emerging new material application requirements, for example as flexible and wearable electronics. The book is structured and organized by the rubber/elastomer type: each chapter describes a d...
Vols. for 1963- include as pt. 2 of the Jan. issue: Medical subject headings.
The second edition of this very successful book documents the latest progress in the prevention, diagnosis and treatment of esophageal cancer and includes additional sections covering novel targeted therapeutic approaches, immunotherapy and palliative and nutritional support for patients. Furthermore, the sections covering epidemiology, molecular biology, pathology, staging and radiologic and endoscopic assessments have been thoroughly updated and expanded. The principles of surgical resection, radiation therapy and systemic therapy are reviewed and attention is paid to the multidisciplinary approaches to the management of early stage cervical, thoracic, distal and junctional tumors. Updated information is also provided on the treatment of metastatic and recurrent disease as well as approaches that may impact future care, such as chemoprevention. Esophageal Cancer: Prevention, Diagnosis and Therapy will assist specialists from various disciplines, including surgery, radiation therapy, gastroenterology, medical oncology and palliative medicine, in delivering optimal, up-to-date care to the benefit of patients.
This book provides a multidisciplinary perspective (ranging from chemistry to physics and biology) of the current research and applications of organic and hybrid photonic crystals. The authors detail the chemical and physical tools used to develop organic photonic crystals, explain methods for engineering new nano-structures, and propose novel physical phenomena or technological applications based on such materials. Organic and Hybrid Photonic Crystal lasers, sensors, photovoltaic devices and stimuli responsive devices are discussed.
The contributors to the book are world best experts in the optics of random media; they provide a state-of-the-art review of recent developments in the field including nonlinear optical and magneto-optical properties, Raman and hyper-Raman scattering, laser action, plasmon excitation and localized giant fields, imaging and spectroscopy of random media
This Research Topic is part of a series with, "Bioinformatics Analysis of Omics Data for Biomarker Identification in Clinical Research - Volume I" (https://www.frontiersin.org/research-topics/13816/bioinformatics-analysis-of-omics-data-for-biomarker-identification-in-clinical-research) The advances and the decreasing cost of omics data enable profiling of disease molecular features at different levels, including bulk tissues, animal models, and single cells. Large volumes of omics data enhance the ability to search for information for preclinical study and provide the opportunity to leverage them to understand disease mechanisms, identify molecular targets for therapy, and detect biomarkers ...