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The scientific advances in the physiology and pathophysiology of adipose tissue over the last two decades have been considerable. Today, the cellular and molecular mechanisms of adipogenesis are well known. In addition, adipose tissue is now recognized as a real endocrine organ that produces hormones such as the leptin acting to regulate food intake and energy balance in the central nervous system, a finding that has completely revolutionized the paradigm of energy homeostasis. Other adipokines have now been described and these molecules are taking on increasing importance in physiology and pathophysiology. Moreover, numerous works have shown that in obesity, but also in cases of lipodystoph...
At publication date, a free ebook version of this title will be available through Luminos, University of California Press’s Open Access publishing program. Visit www.luminosoa.org to learn more. Want. Disease. Ignorance. Squalor. Idleness. Taken together, these comprise the “giant evils” expressed in the Social Question—first raised in mid-nineteenth-century Europe to diagnose the crises produced by the emergence of the industrial society. Due to a globalized switch to neoliberalism in the final quarter of the twentieth century, the Social Question has made a worldwide comeback. The Social Question in the Twenty-First Century maps out the linked crises across regions and countries an...
This book constitutes the refereed proceedings of the 17th European Conference on Machine Learning, ECML 2006, held, jointly with PKDD 2006. The book presents 46 revised full papers and 36 revised short papers together with abstracts of 5 invited talks, carefully reviewed and selected from 564 papers submitted. The papers present a wealth of new results in the area and address all current issues in machine learning.
Dieses Fachbuch erläutert die molekularen Grundlagen von Entzündungen, spannt den Bogen zu Infektionskrankheiten und den Zusammenhang zwischen Entzündungen und chronischen Erkrankungen, behandelt abschließend den Heilungsprozess und zeigt Therapiemöglichkeiten.
What can we learn about collective action across Central and Eastern Europe by focusing on activism within urban spaces? This volume argues that the recent resurgence of urban grassroots mobilisation represents a new phase in the development of post-socialist civil societies and that these civil societies have significantly more vitality than is commonly perceived. The case studies here reflect the diversity and complexity of post-socialist urban movements, capturing also the extent to which the laboratory of urban politics is richly illustrative of the complex nexus of state-society-market relations within post-socialism. The grassroots campaigns and actions reflect the new social cleavages and increased polarisation as a consequence of neoliberal urbanisation and global integration, as well as the transformation of state power and authority in the region. Studying urban activism in Central and Eastern Europe is instructive for urban movements scholars generally, as it forces us to acknowledge the variety of forms that contention can take and the usefulness of embedding the study of urban movements within a larger understanding of civil society.
Despite decades under Putin's rule, it is too simplistic to assert that authoritarianism in Russia has eliminated activism, especially in relation to everyday life. Instead, we must build an awareness of diverse efforts to mobilize citizens to better understand how activism is shaped by and, in turn, shapes the regime. Varieties of Russian Activism focuses on a broad range of collective actions addressing issues from labor organizing to housing renovation, religion, electoral politics, minority language rights, and urban planning. Contributors draw attention to significant forms of grassroots politics that have not received sufficient attention in scholarship or that deserve fresh examination. The volume shows that Russians find novel ways to redress everyday problems and demand new services. Together, these essays interrogate what kinds of practices can be defined as activism in a fast-changing, politically volatile society. An engaging collection, Varieties of Russian Activism unites leading scholars in the common aim of approaching the embeddedness of civic activism in the conditions of everyday life, connectedness, and rising society-state expectations.
Type 2 diabetes afflicts 250 million people worldwide, creating life-threatening and debilitating health effects. Written from a surgeon’s perspective, this book is designed to provide information on the physical and socioeconomic underpinnings of the disease, as well as causes and complications based on case histories. It includes suggestions to avoid or delay the onset of the disease, and to minimize complications for those already afflicted.
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When the leptin gene was discovered in 1994, news articles predicted that there might soon be an easy, pharmaceutical solution to the growing public health crisis of obesity. Yet this scientific breakthrough merely proved once again how difficult the fight against fat really is. Despite the many appetite-suppressants, diet pills, and weight-loss programs available today, approximately 30 percent of Americans are obese. And that number is expanding rapidly. Fat is the engaging story of the scientific quest to understand and control body weight. Covering the entire twentieth century, Robert Pool chronicles the evolving blame-game for fat--from being a result of undisciplined behavior to subcon...