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Now in a revised and expanded third edition, this case-based guide emphasizes the latest investigative advances in both imaging and molecular diagnostics and new treatment approaches for a wide variety of common and complex endocrine conditions. Utilizing unique clinical case histories, each main endocrine condition and disorder is curated by a senior Section Editor with an introduction to his or her area covering both physiology and pathophysiology. This introductory chapter is followed by a number of case histories written by invited experts and designed to cover the important relevant pathophysiology, following a consistent chapter format for ease of use, including bulleted objectives, ca...
Obesity is a global epidemic and an urgent health crisis impacting human health and health services, with the economic consequences of loss of human capital. It is a crisis for health professionals, health economists and government officials managing finite resources and the economy with premature loss of life and economic productivity. In this Frontiers Research Topic, researchers from a breadth of disciplines internationally contributed reviews, meta-analyses and novel data on the challenges obesity presents in attempts to stimulate debate on strategies and solutions for this crisis.
Now in its fifth edition, 'Fast Facts: Diabetes Mellitus' continues to grow in popularity as essential reading for all healthcare professionals. As well as providing a practical approach to the causes and clinical manifestations of types 1 and 2 diabetes, it is packed with information on early detection, and comprehensive details of the latest drug therapies, insulin regimens, delivery methods and injection sites. Importantly, this effective handbook provides simple clear messages to give to your patients to maximize their self-management skills. All healthcare professionals can have a significant life-altering effect on the health outcomes and quality of life of people living with diabetes,...
The world is witnessing a burgeoning global epidemic of chronic cerebro- and cardiovascular disease and depression disorders. The reader will find this comprehensive book to be a long-needed, up-to-date knowledge base on these increasingly recognized comorbid conditions that have long-term consequences for individual function and well-being and society in general. This comprehensive book outlines the complex and bidirectional relationship between various types of depression and cerebro- and cardiovascular diseases. It is written by a range of experts in the field, including psychiatrists, cardiologists, neuroscientists, psychologists, and epidemiologists, with the aim of presenting and discu...
Recent years have seen a substantial increase in both academic and clinical interest around how ‘lifestyle behaviors’, such as exercise, sleep and diet, can influence mental health. The aim of this Research Topic is to produce a novel body of work contributing towards the field of ‘Lifestyle Psychiatry’; i.e. the use of lifestyle interventions in the treatment of mental disorders. In this way, the Research Topic aims to (a) present important ‘behavioral targets’ for lifestyle modification in public health and/or clinical settings, and (b) examine the efficacy and implementation of lifestyle interventions for people with mental health conditions. Collectively, this research presented within this Research Topic can increase understanding and inform evidence-based practice of ‘Lifestyle Psychiatry’, while providing clear directions for future research required to take the field forward.
The Essential Guide to Recognizing and Treating Acute Endocrine and Metabolic Illness Endocrinology covers some of the most common conditions and serious public health challenges facing medicine today, and endocrine and metabolic emergencies constitute a large proportion of the clinical workload. Endocrine and Metabolic Medical Emergencies: A Clinician’s Guide provides a singular reference to help endocrinologists, acute and general medicine clinicians, hospitalists and critical care physicians, and general practitioners recognize the symptoms of endocrine emergencies and provide the highest standards of care. Already the definitive and most comprehensive guide to endocrine emergency care,...
NAFLD and NASH refer to the hepatic phenotype of metabolic syndromes strongly associated with obesity, diabetes, and dyslipidemia. NAFLD and NASH have complex pathogenesis modulated not only by the liver but also by muscle, adipose tissue, pancreas, gut microbiome, and immune and central nervous systems. This complex pathology, coupled with insulin resistance, lipid and bile acid changes, and congenital genetic predisposition, induces liver injury due to oxidative stress, endoplasmic reticulum stress, and autophagy dysfunction. Additionally, NAFLD and NASH contribute to diseases such as cirrhosis, atherosclerosis, chronic kidney disease, lung disease, and cancer in various organs, leading to...
Given the success of the previous collection Pharmacological and Non-Pharmacological Therapy for Obesity and Diabetes, we are pleased to announce the launch of Volume II. Overweight and obesity are defined as abnormal or excessive fat accumulation that may induce inflammation and impair health, leading to metabolic syndrome and diabetes. Their prevalence is increasing and is considered a major public health concern in the 21st century. While numerous mechanisms have been proposed for this epidemic of obesity, it is well agreed upon that lack of physical activity and high calorie intake plays causal roles. Understanding the causes that lead to obesity and also its prevention or reversion are of public health priority. This could be managed by either modification of lifestyle (through physical activity to restore energy balance or reduction of calorie intake, proper diet that is rich in fiber, increasing energy outlay) or using adequate medication.