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Advancing the Discipline of Regulatory Science for Medical Product Development
The field of endeavors known as "regulatory science" has grown out of the need to link and integrate knowledge within and among basic science research, clinical research, clinical medicine, and other specific scientific disciplines whose focus, aggregation, and ultimate implementation could inform biomedical product development and regulatory decision making. Substantial efforts have been devoted to defining regulatory science and communicating its value and role across the scientific and regulatory ecosystems. Investments are also being made in technology infrastructure, regulatory systems, and workforce development to support and advance this burgeoning discipline. In October 2015, the Nat...
Recycling of Used Lead-Acid Batteries
This document includes a pragmatic framework for designing representative studies and developing uniform sampling guidelines to support estimates of morbidity that are explicitly linked to exposure to land-based contaminants from used lead acid battery recycling (ULAB) activities. A primary goal is to support environmental burden of disease evaluations, which attempt to attribute health outcomes to specific sources of pollution. The guidelines provide recommendations on the most appropriate and cost-effective sampling and analysis methods to ensure the collection of representative population-level data, sample size recommendations for each contaminant and environmental media, biological samp...
Artisanal Small-Scale Gold Mining
This framework document provides a pragmatic approach for designing representative studies and developing uniform sampling guidelines to support estimates of morbidity that are explicitly linked to exposure to land-based contaminants from small-scale artisanal gold mining activities. A primary goal is to support environmental burden of disease evaluations, which attempt to attribute health outcomes to specific sources of pollution. The guidelines provide recommendations on the most appropriate and cost-effective sampling and analysis methods to ensure the collection of representative population-level data, sample size recommendations for each contaminant and environmental media, biological s...
Modelling of Pollutants in Complex Environmental Systems
Environmental modelling has enjoyed a long tradition, but there is a defined need to continually address both the power and the limitations of such models, as well as their quantitative assessment. This book showcases modern environmental modelling methods, the basic theory behind them and their incorporation into complex environmental investigations. It highlights advanced computing technologies and how they have led to unprecedented and adaptive modelling, simulation and decision-support tools to study complex environmental systems, and how they can be applied to current environmental concerns. This volume is essential reading for researchers in academia, industry and government-related bo...
A Research Review of Interventions to Increase the Persistence and Resilience of Coral Reefs
Coral reef declines have been recorded for all major tropical ocean basins since the 1980s, averaging approximately 30-50% reductions in reef cover globally. These losses are a result of numerous problems, including habitat destruction, pollution, overfishing, disease, and climate change. Greenhouse gas emissions and the associated increases in ocean temperature and carbon dioxide (CO2) concentrations have been implicated in increased reports of coral bleaching, disease outbreaks, and ocean acidification (OA). For the hundreds of millions of people who depend on reefs for food or livelihoods, the thousands of communities that depend on reefs for wave protection, the people whose cultural pra...
Assessment and Management of Environmental Risks
Managing environmental contamination requires decision makers to weigh eXlstmg risks against the potential effects of implementing environmental policies - considering both the benefits and disruptions that may result from different actions. The NATO Advanced Research Workshop in Lisbon was an important step in the development and application of cost efficient methods of risk assessment especiaIly within the constraints of a budget. The goal of the workshop was to evaluate the potential for risk assessment to serve as a unified and unifying technique in addressing a wide range of environmental problems. Papers presented in this book discuss issues ranging from specific and local studies (spe...
Roman Artists, Patrons, and Public Consumption
A fascinating shift toward more nuanced interpretations of Roman art that look at different kinds of social knowledge and local contexts
The Economist's View of the World
A thought-provoking tour of the economist's mind using non-technical language and relevant political examples throughout.
Campus Martius
A mosquito-infested and swampy plain lying north of the city walls, Rome's Campus Martius, or Field of Mars, was used for much of the period of the Republic as a military training ground and as a site for celebratory rituals and occasional political assemblies. Initially punctuated with temples vowed by victorious generals, during the imperial era it became filled with extraordinary baths, theaters, porticoes, aqueducts, and other structures - many of which were architectural firsts for the capitol. This book explores the myriad factors that contributed to the transformation of the Campus Martius from an occasionally visited space to a crowded center of daily activity. It presents a case study of the repurposing of urban landscape in the Roman world and explores how existing topographical features that fit well with the Republic's needs ultimately attracted architecture that forever transformed those features but still resonated with the area's original military and ceremonial traditions.
The Brummer Galleries, Paris and New York
This is the first thorough investigation of the Brummer brothers’ remarkable career as dealers in antiques, curiosities and modernism in Paris and New York over six decades (1906-1964). A dozen specialists aggregate their expertise to explore extant dealer records and museum archives, parse the wide-ranging Brummer stock, and assess how objects were sourced, marketed, labelled, restored, and displayed. The research provides insights into emerging collecting fields as they crystallised, at the crossroads between market and museum. It questions the trope of the tastemaker; the translocation of material culture, and the dealers’ prolific relationships with illustrious collectors, curators, scholars, artists, and fellow dealers.
