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This book provides health professionals and scientists with a comprehensive overview of the mesothelioma - an asbestos induced malignancy. It includes chapters on epidemology, diagnosis, histopathology, radiology, surgery, chemotherapy, immune therapy, and radiotherapy as well as the molecular biology and future therapies.
A link between inflammation and cancer has been established many years ago, yet it is only recently that the potential significance of this connection has become apparent. Although several examples of chronic inflammatory conditions, often induced by persistent irritation and/or infection, developing into cancer have been known for some time, there has been a notable resistance to contemplate the possibility that this association may apply in a causative way to other cancers. Examples for such progression from chronic inflammation to cancer are colon carcinoma developing with increased frequency in patients with ulcerative colitis, and the increased incidence of bladder cancer in patients su...
The Advances in Cancer Research series provides invaluable information on the exciting and fast-moving field of cancer research. This volume presents outstanding and original reviews on a variety of topics, including gene expression in inherited breast cancer, multiparameter analyses of cell cycle regulation in tumorigenesis, Rho GTPases in transformation and metastasis, the myc oncogene, genetic requirements for the episomal maintenance of oncogenic herpesvirus genomes, treatment of Epstein-Barr virus-associated malignancies with specific T cells, the role of glycogen synthase kinase-3 in cancer, chronic immune activation and inflammation in the pathogenesis of AIDS and cancer, and molecula...
Cancer is a major public health concern and one of the leading causes of death. There is no simple solution for this complex disease, therefore interdisciplinary approaches might help to find solutions to many unanswered questions and challenges about cancer. The rapid flow of interdisciplinary research in cancer during recent years has increased our understanding of the nature of cancers. Such interdisciplinary approaches could be helpful for both the diagnosis and the development of more effective therapeutic strategies. The âInterdisciplinary Cancer Researchâ series publishes comprehensive volumes on different cancers and presents the most updated and peer-reviewed articles on human c...
Dr. Koguchi receives funding from Tesaro, a GSK company, Bristol-Myers Squibb, and Shimadzu Corporation.. Dr. Vujanovic is a co-inventor of a methodology licensed to INmune Bio, Inc. where a selective inhibitor of soluble TNF can be used to prevent or treat malignancies. Dr. Hansen is the recipient of a private grant from Eurostars Eureka. The other Topic Editors declare no competing interests.
A concise summary of the most important clinical trials in cardiac and thoracic surgery. The focus is on how evidence-based decision making has helped to shape modern practice and guidelines. The key trials are described and an overview of their impact provided. Much research has been undertaken to study the efficacy of different drugs, techniques, and treatment strategies within cardiothoracic surgery. As a result, many randomised controlled trials have been published which discuss a wide variety of topics and with the intention of improving current practice and patient care. This volume presents a selection of the key trials and assesses their impact. Compact and easy to read, the distillation of core information will enable the reader to understand the importance of the key papers that have influenced best practice across operating theatres, clinics, multi-disciplinary meetings, and inpatient management. Including full summaries of more than 30 trials and reflecting the clinical scenarios encountered in everyday practice by cardiothoracic surgeons, this concise volume is written for both trainee and more experienced members of the surgical team.