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Complement and Immunotherapeutics
  • Language: en
  • Pages: 222

Complement and Immunotherapeutics

None

Function and Dysfunction of Complement Factor H
  • Language: en
  • Pages: 175

Function and Dysfunction of Complement Factor H

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Updates on the Complement System in Kidney Diseases
  • Language: en
  • Pages: 172

Updates on the Complement System in Kidney Diseases

None

Current Challenges in Complement Diagnostics
  • Language: en
  • Pages: 364

Current Challenges in Complement Diagnostics

The complement system is an important innate immune surveillance network that has a key role in protecting our bodies against pathogens and other threats. It is a highly complex system consisting of approximately 50 soluble and cell surface-bound proteins that interact to eliminate danger signals. These signals include factors such as invading microorganisms, necrotic cells, and immune complexes. Furthermore, complement can link innate and adaptive immune responses by regulating T cell and B cell responses. The complement system is tightly regulated to avoid uncontrolled activation. Dysregulation of the complement system has been linked to numerous diseases, both rare and common. Uncontrolle...

Immunity and Inflammatory Responses in Kidney Disease: from Mechanisms to Novel Therapeutic Strategies
  • Language: en
  • Pages: 237

Immunity and Inflammatory Responses in Kidney Disease: from Mechanisms to Novel Therapeutic Strategies

Kidney disease is a leading cause of death worldwide and is increasingly recognized as a global health problem. The kidneys are a frequent target of systemic immune and autoimmune disorders, including systemic autoimmunity and vasculitis, immune complex-related serum sickness, and complement disorders. The complex regulation between the immune system and inflammation plays a key role in the progression of kidney disease, especially in immune-related nephropathy. Cytokines released by monocytes/macrophages, including IL-17, INF-γ, TNF, and IL-6, exacerbate renal dysfunction and injury. M1 pro-inflammatory cells help to clear infections but can also promote renal injury and lead to renal fibr...

Register of Commissioned and Warrant Officers of the United States Navy and Reserve Officers on Active Duty
  • Language: en
  • Pages: 646
Management in Museums
  • Language: en
  • Pages: 316

Management in Museums

  • Type: Book
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  • Published: 1999-01-01
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  • Publisher: A&C Black

Management in museums has become a key issue in the past decade, a reflection of the challenges that museums face in operating in a a rapidly changing environment. Research in this field has developed significantly and this volume brings together some major contributions. The authors are either academics in the management field or museum managers themselves, the latter reflecting either on museum practice in the general, or utilising organisational theory to analyse their personal experiences.

Proceedings at the Election for the City of Dublin
  • Language: en
  • Pages: 172

Proceedings at the Election for the City of Dublin

  • Type: Book
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  • Published: 1835
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  • Publisher: Unknown

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Public Administration Review
  • Language: en
  • Pages: 982

Public Administration Review

  • Type: Book
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  • Published: 2002
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  • Publisher: Unknown

Includes section "Reviews of books and documents."