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Circadian Control of Immunity
We acknowledge the initiation and support of this Research Topic by the International Union of Immunological Societies (IUIS). We hereby state publicly that the IUIS has had no editorial input in articles included in this Research Topic, thus ensuring that all aspects of this Research Topic are evaluated objectively, unbiased by any specific policy or opinion of the IUIS.
Bone Marrow Niche
This volume summarizes recent advances in research on mesenchymal cell populations in the bone marrow. It explores how mesenchymal cells create niches for immune cells in extramedullary organs and it discusses new concepts of lympho-hematopoietic microenvironments. Readers are introduced to the fundamentals of hematopoietic stem cells (HSCs) differentiation to all types of blood cells, including immune cells, in the bone marrow. The book highlights how this process is supported and regulated by the individual microenvironments of stem cells, termed niches. The identity of HSC niches has been subject to longstanding debates. Recent studies identified the population of mesenchymal stem cells as the major cellular component of niches, for hematopoietic stem and progenitor cells (HSPCs) and their candidate developmental origin. Furthermore, candidate cellular niches for immune cells in lymph nodes and adipose and connective tissues were identified. The authors of this volume focus on shared features between those and HSPC niche cells in the bone marrow. Covering latest research results, this book serves as fascinating read for researchers and clinicians in hematology and immunology.
Hematopoietic Stem Cell Biology
In the summer of 1988, my developmental biology professor announced to the class that hematopoietic stem cells (HSCs) had finally been purified. Somehow, I never forgot the professor’s words. When I started working in Dr. Irv Weissman’s labo- tory at Stanford as a postdoctoral fellow, I realized that the findings mentioned by the professor were from Weissman’s laboratory and had been published in a 1988 edition of the journal Science. It has been over 20 years since the publication of that seminal paper, and since then tremendous advances in understanding the biology and maturation of HSCs, namely the process of hematopoiesis, which includes lymphocyte development, have been made. Thes...
Neural Information Processing
The two volume set LNCS 4984 and LNCS 4985 constitutes the thoroughly refereed post-conference proceedings of the 14th International Conference on Neural Information Processing, ICONIP 2007, held in Kitakyushu, Japan, in November 2007, jointly with BRAINIT 2007, the 4th International Conference on Brain-Inspired Information Technology. The 228 revised full papers presented were carefully reviewed and selected from numerous ordinary paper submissions and 15 special organized sessions. The 116 papers of the first volume are organized in topical sections on computational neuroscience, learning and memory, neural network models, supervised/unsupervised/reinforcement learning, statistical learning algorithms, optimization algorithms, novel algorithms, as well as motor control and vision. The second volume contains 112 contributions related to statistical and pattern recognition algorithms, neuromorphic hardware and implementations, robotics, data mining and knowledge discovery, real world applications, cognitive and hybrid intelligent systems, bioinformatics, neuroinformatics, brain-conputer interfaces, and novel approaches.
Gamma-delta T Cells
Over the last 15 years, since the discovery of the T cell receptor and genes, rapid progress has been made toward the understanding of the biology of T cells. They differ from conventional T cells not only in T cell receptor composition, but also in their development, tissue distribution, and physiological functions. This volume contains seven chapters contributed by experts on different aspects of T cells, including the natural ligands for T cell receptors, IL-7-dependent regulation of T cell development, cytokine-mediated inter-cellular communication of T cells with other cell types, and their physiological functions in innate and adaptive immune responses. The comprehensive review articles collected in this volume will be of interest to basic immunologists who wish to update their knowledge on the biology of T cells. The book also provides a unique opportunity for non-immunologists and clinicians to understand how the immune system is specifically equipped to protect the body against pathogens at the environmental interface.
Progress in Neural Information Processing
These two volumes are the papers presented at the International Conference on Neural Information Processing (ICONIP'96) held in Hong Kong, 24-27 September 1996. Over three hundred selected papers make up two volumes of 700 pages each. Featured topics of Volume 1 are Learning Theories and Algorithms, Speech and Signal Processing, Pattern Recognition and Image Processing, Recurrent Networks, Automata and Dynamics. Volume 2 focusses on Financial Engineering and Time Series Forecasting, Evolutionary Computing, Neurosciences and Biophysics, Neural Control and Robotics, Hardware Implementations, Hybrid Systems and Applications, plus a number of Special Sessions. Other topics covered include image processing, computer vision, fuzzy logic, pattern recognition, algorithms and architectures, and financial engineering. These two volumes combine to cover the major topics in neural information processing and reflect the latest progress with a good balance between scientific studies and industrial applications, a well as featuring neural information processing approaches on financial engineering.
