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Global economic forces underpin political and social issues and have real impacts on the quality of life in local communities, cities, states and regions. In the face of potential volatility, leaders in every ‘place’ concern themselves with how they can ensure local economic resiliency for present and future generations. This book argues for the strategic management of places through intentional public policy that brings together stakeholders from the public, private and nonprofit sectors to create an inclusive and sustainable economic path forward. While many economists and political scientists have proposed one-size-fits-all approaches, this book puts forward a more holistic approach, giving local leaders and policymakers the tools to take inventory of their local contexts and providing case study examples of how to craft public policies that create prosperous and sustainable economic conditions.
This book represents the first multidisciplinary scientific work on a deep volcanic maar lake in comparison with other similar temperate lakes. The syntheses of the main characteristics of Lake Pavin are, for the first time, set in a firmer footing comparative approach, encompassing regional, national, European and international aquatic science contexts. It is a unique lake because of its permanently anoxic monimolimnion, and furthermore, because of its small surface area, its substantially low human influence, and by the fact that it does not have a river inflow. The book reflects the scientific research done on the general limnology, history, origin, volcanology and geological environment as well as on the geochemistry and biogeochemical cycles. Other chapters focus on the biology and microbial ecology whereas the sedimentology and paleolimnology are also given attention. This volume will be of special interest to researchers and advanced students, primarily in the fields of limnology, biogeochemistry, and aquatic ecology.
A timely update of a highly popular handbook on statistical genomics This new, two-volume edition of a classic text provides a thorough introduction to statistical genomics, a vital resource for advanced graduate students, early-career researchers and new entrants to the field. It introduces new and updated information on developments that have occurred since the 3rd edition. Widely regarded as the reference work in the field, it features new chapters focusing on statistical aspects of data generated by new sequencing technologies, including sequence-based functional assays. It expands on previous coverage of the many processes between genotype and phenotype, including gene expression and ep...
This book provides a thorough description of hexapod external fixators, from the theoretical basis to their practical application. Indications and practical use in current Orthopaedic practice are addressed in detail, offering the reader essential insights into the strengths and limitations of these devices. The main aspects covered, include primary (congenital) and secondary (acquired) deformities of the limbs: the etiology, pathomechanics, clinics, technical “tips and tricks” and suggested frame assemblies are presented. Each chapter addresses a specific Orthopaedic problem and includes representative clinical cases commented on by the authors. Illustrations and X-ray images support th...
The fourth edition of this well-received book offers a comprehensive update on recent developments and trends in the clinical and scientific applications of multislice computed tomography. Following an initial section on the most significant current technical aspects and issues, detailed information is provided on a comprehensive range of diagnostic applications. Imaging of the head and neck, the cardiovascular system, the abdomen, and the lungs is covered in depth, describing the application of multislice CT in a variety of tumors and other pathologies. Emerging fields such as pediatric imaging and CT-guided interventions are fully addressed, and emergency CT is also covered. Radiation expo...
In the Christian art of western Europe images survive from as early as the sixth century that show figures of founders or donors bearing a model of the building they caused to be constructed, renovated or embellished. Previous studies have tended to turn on the question of how accurately these models represent the buildings they were intended to portray. But the donors' model cannot be explained exclusively by comparison with its built equivalent. The sculptors, goldsmiths, minters, mosaicists, painters, weavers and sealmakers who created these little buildings were not always aiming to produce a straightforward likeness of the edifice in question but rather to represent its significance. Th...
This volume presents different aspects related to bioactive compounds, starting with their natural state in raw sources, physicochemical characterization and employment in pharmacy and medicine. The volume is divided into three parts. The first part describes the chemicals structure of bioactive compounds from different natural sources such as olive oils, wines, and medicinal plants. Special attention has been given to identifying the bioactive composition within variations of these natural sources (for example, extra virgin, ordinary or lampante olive oils). The second part of the volume presents the principal methods used for detecting, identifying and quantifying bioactive compounds. Emph...
The mosaics in the collection of the J. Paul Getty Museum span the second through the sixth centuries AD and reveal the diversity of compositions found throughout the Roman Empire during this period. Elaborate floors of stone and glass tesserae transformed private dwellings and public buildings alike into spectacular settings of vibrant color, figural imagery, and geometric design. Scenes from mythology, nature, daily life, and spectacles in the arena enlivened interior spaces and reflected the cultural ambitions of wealthy patrons. This online catalogue documents all of the mosaics in the Getty Museum’s collection, presenting their artistry in new color photography as well as the contexts...