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Gauge Theories, Applied Supersymmetry And Quantum Gravity Ii - Proceedings Of The Workshop
This volume contains the proceedings of a meeting held at Imperial College which is devoted to recent developments in string theory, supersymmetry and quantum gravity. The volume comprises two different sections. The first consists of five pedagogical reviews by prominent physicists, covering the currently important subjects of supermembranes, duality, D-branes, new non-perturbative methods and string phenomenology. The second section consists of research reports in these areas and also on other currently important topics such as supersymmetric gauge theories, two-dimensional quantum gravity and black holes.
Dendritic Cells
Since their discovery in 1973 by Zanvil Cohn and Ralph Steinman (Nobel Prize in Physiology and Medicine, 2011), dendritic cells (DCs) continue to intrigue research scientists as their new markers, subpopulations and properties are being detected and the relevant literature is being doubled each year. This book combines the most comprehensive reviews of several critical aspects of DC biology and function written by a group of international experts in the field. The first section briefly discusses recent advances in DC subtypes, phenotypes, and functions in different diseases. The following sections look closely at DC phenotyping, DC-NK cell interplay, and roles of DC in bone loss and repair and parasitic infections. The final section on DC and cancer includes perspectives on DC vaccination based on modifications and therapeutic applications.
Computational Methods for Molecular Imaging
This volume contains original submissions on the development and application of molecular imaging computing. The editors invited authors to submit high-quality contributions on a wide range of topics including, but not limited to: • Image Synthesis & Reconstruction of Emission Tomography (PET, SPECT) and other Molecular Imaging Modalities • Molecular Imaging Enhancement • Data Analysis of Clinical & Pre-clinical Molecular Imaging • Multi-Modal Image Processing (PET/CT, PET/MR, SPECT/CT, etc.) • Machine Learning and Data Mining in Molecular Imaging. Molecular imaging is an evolving clinical and research discipline enabling the visualization, characterization and quantification of biological processes taking place at the cellular and subcellular levels within intact living subjects. Computational methods play an important role in the development of molecular imaging, from image synthesis to data analysis and from clinical diagnosis to therapy individualization. This work will bring readers from academia and industry up to date on the most recent developments in this field.
Simulation and Synthesis in Medical Imaging
This book constitutes the refereed proceedings of the 5th International Workshop on Simulation and Synthesis in Medical Imaging, SASHIMI 2020, held in conjunction with MICCAI 2020, in Lima, Peru, in October 2020. The 19 full papers presented were carefully reviewed and selected from 27 submissions. The contributions span the following broad categories in alignment with the initial call-for-papers: methods based on generative models or adversarial learning for MRI/CT/PET/microscopy image synthesis, and several applications of image synthesis and simulation for data augmentation, image enhancement or segmentation.
Approaches to Advance Cancer Vaccines to Clinical Utility
Although cancer vaccines have yielded promising results both in vitro and in animal models, their translation into clinical application has not been very successful so far. Through the success of immune checkpoint inhibitors, the tumor immunotherapy field revived and led to important new insights. A better understanding of the functional capacity of different dendritic cell (DC) subsets and the immunogenicity of tumor antigens, more particularly of neoantigens, have important implications for the improvement of cancer vaccines. These insights can guide the development of novel strategies, to enhance the clinical utility of cancer vaccines. The aim of this Research Topic is therefore to provide a comprehensive overview of current issues regarding cancer vaccine development with an emphasis on novel approaches toward enhancing their efficacy.
Strings '93 - Proceedings Of The Conference
This volume gives an up-to-date account of the major activities in the general area of string theory. String phenomenology, mirror symmetry, duality black hole physics, topological and conformal field theory, 2D gravity and QCD related developments are reviewed in detail.
Artificial Intelligence and PET Imaging, Part 1, An Issue of PET Clinics
Artificial Intelligence and PET Imaging, Part 1, An Issue of PET Clinics, E-Book
Investigating Cellular Nanoscale with X-rays
The advances and technical improvements of X-ray imaging techniques, taking advantage of X-ray focussing optics and high intensity synchrotron sources, nowadays allow for the use of X-rays to probe the cellular nanoscale. Importantly, X-rays permit thick samples to be imaged without sectioning or slicing. In this work, two macromolecules, namely keratin intermediate filament (IF) proteins and DNA, both essential components of cells, were studied by X-ray techniques. Keratin IF proteins make up an integral part of the cytoskeleton of epithelial cells and form a dense intracellular network of bundles. This network is built from monomers in a hierarchical fashion. Thus, the keratin structure fo...
The Marathon of the Messenger
The Covid-19 pandemic changed the world. Indeed a real race took place worldwide between SARS-CoV-2 on the one hand and researchers on the other – especially those specializing in messenger RNA vaccines. Four years after its emergence, the pandemic is not over, but some decisive battles have been won, thanks to the great success of mRNA vaccines. The Marathon of The Messenger presents the history of these mRNA vaccines, combining a scientific background with historical and economic perspectives. It appears that an important page in the history of these new vaccines was written in Europe, thanks to the crucial work of German and French scientists; this effort began in 1993 and continues to ...
