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This is the third in the five-yearly series of surveys of what is happening in rock art studies around the world. As always, the texts reflect something of the great differences in approach and emphasis that exist in different regions. The volume presents examples from Europe, Asia, Africa, and the New World. During the period in question, 1999 to 2004, there have been few major events, although in the field of Pleistocene art many new discoveries have been made, and a new country added to the select list of those with Ice Age cave art. Some regions such as North Africa and the former USSR have seen a tremendous amount of activity, focusing not only on recording but also on chronology, and the conservation of sites. With the global increase of tourism, the management of rock art sites that are accessible to the public is a theme of ever-growing importance.
This volume covers a broad range of methods, technologies, and protocols on malaria. Chapters detail research on collecting parasites in the field, single molecule-level analyses of adhesive interactions, and focused studies aiming at disrupting the devastating disease. Written in the format of the highly successful Methods in Molecular Biology series, each chapter includes an introduction to the topic, lists necessary materials and reagents, includes tips on troubleshooting and known pitfalls, and step-by-step, readily reproducible protocols. Authoritative and cutting-edge, Malaria Immunology: Targeting the Surface of Infected Erythrocytes aims to be a useful and practical guide to researches to help further their study in this field. Chapter Analysis of var gene transcription pattern using DBLα-tags [Chapter 14] is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.
In a state-of-the-art synthesis of basic science and clinical practice, Roy Smith and a distinguished panel of researchers and clinicians review GH regulation and its action at the molecular level, and describe the basis for GH deficiency and the use of GH as therapy in a variety of clinical situations. The clinical presentation moves beyond the treatment of GH-deficient children to include the genetics of GH-deficiency, GH-deficiency in adults, osteoporosis, Syndrome X, sleep quality, GH in AIDS patients, GHRH in clinical studies. Timely and innovative, Human Growth Hormone: Research and Clinical Practice will benefit both basic and clinical researchers, as well as those clinical endocrinologists who want to use growth hormone not only in treating children, but also in treating adult disorders, including those associated with metabolic disease.
Knowledge integration-the purposeful combination of specialized and complementary knowledge to achieve specific tasks-is increasingly important for organizations. This book offers a consistent set of ideas, methods and tools useful to interpret, analyze and act upon the processes of knowledge integration across organizational and other boundaries.
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The purpose of this book, which is written mainly for pharmacothera pists, is to draw the physician's attentions, through specific examples, to iatrogenic (i.e., diagnostically or therapeutically induced) carcino genesis. The book is not intended, however, to arouse public concern. It has been known for some time that each therapeutic measure has a risk-benefit ratio, the estimation of which requires an understanding of carcinogenic side-effects. The number of iatrogenic tumors published so far is not large; however, we assume that there are a number of cases that have not been registered. In the past it was not generally recognized that medical treatment might involve carcinogenic risks; mo...
**Selected for Doody's Core Titles® 2024 in Ophthalmology**Nanotechnology in Ophthalmology is a comprehensive and up-to-date reference on the role and applications of nanotechnology in ophthalmology, from drug delivery and treatment of ocular diseases to toxicity issues. Written by experts from the nanotechnology, ophthalmology, and pharmacology fields, this book has a unique, broad and diverse scope, including chapters on nanosensor-based diagnostic tools, delivery of nanobiomaterials, implantable materials and devices, delivery of nanobiomaterials, nanotechnology for medical and surgical treatment, regenerative medicine, and more. This book provides a valuable reference to researchers working in the areas of ophthalmology, nanoscience and pharmacology, and clinical fellows who are interested in nanoophthalmology as a reference for their practice and research. - Provides a comprehensive review of the literature in the area of nanoophthalmology - Discusses regenerative medicine, drug delivery, imaging, and medical device applications - Analyzes treatment strategies for emerging and multidrug-resistant ocular pathogens
Renowned experts present the latest knowledge in ... In this volume of Developments in Ophthalmology, a panel of renowned glaucoma surgeons reports its findings and the updated evidence-based literature data on indications, outcomes, pearls and pitfalls of techniques in which they all have an undisputable 'hands-on' everyday experience. The publication begins with chapters on conventional procedures, i.e. trabeculectomy (still the gold standard), deep sclerectomy, and glaucoma drainage device implantation explicitly focusing on postoperative management. The role of the ocular surface in glaucoma surgery and the issue of wound healing and its modulation through antimetabolites are further dis...
One of the major findings in the 1992 IPCC report and the 1994 World Meteorological Organization's Ozone Assessment report was the identification of possible climatic effects over the last few decades resulting from anthropogenic ally-induced changes in atmospheric ozone. The initial quantitative estimates of their direct climatic effects indicate significant impacts, though large uncertainties exist and studies using general circulation models are needed. A point that needs to be addressed in particular is that atmospheric ozone differs from greenhouse gases in that it is formed and destroyed by chemical processes in the atmosphere due to interaction involving a large number of source gases...