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Novel Mechanisms of Memory
This book integrates discoveries from recent years to show the diversity of molecular mechanisms that contribute to memory consolidation, reconsolidation, extinction, and forgetting. It provides a special focus on the processes that govern functional and structural plasticity of dendritic spines. In nine chapters, new and important ideas related to learning and memory processes will be presented. Themes discussed include the role of AMPA receptors in memory, two signalling cascades involved in local spine remodelling and memory, the role of extracellular matrix proteins in memory, the regulation of gene expression and protein translation, and mechanisms of retrieval-induced memory modulation and forgetting. We believe that the study of these topics represents a great step toward understanding the complexity of the brain and the processes it governs.
Macromolecular Interplay In Brain Associative Mechanisms
This volume looks at the associative mechanisms of the brain, particularly of the cortico-limbic and diencephalic systems, and also at the macromolecular effects on them, by integrating the contributions of various disciplines converging on one subject and from different points of view. It addresses the question of how so many different activity levels — the biochemical, physiological, and psychological ones — interact in integrative processes. The topics treated include brain reverberating systems and associative phenomena; long-term potentiation, learning, and memory; gene activity and brain activity; and gene expression and information processing during sleep.
Cell Function and Disease
The new experimental tools and approaches of modern biology have allowed us to better understand many fundamental properties of the eukaryotic cells. These significant discoveries have drastically changed the diagnostic and therapeutic approaches of modern clinical practice. On April 18-22, 1988, an International Symposium on Cell Function and Disease was held in Monterrey, Nuevo Leon, Mexico, aimed at reviewing some of the most recent advances made in the following five areas: Genes and Human Diseases; Cellular and Molecular Pathology; Infectious Diseases; Brain Transplants and the New Approaches and Techniques with Potential Application to Cell Function and Disease. This book is based on t...
Transcriptional Regulation by Neuronal Activity
Regulation of gene transcription by neuronal activity is evident in a large number of neuronal processes ranging from neural development and refinement of neuronal connections to learning and response to injury. In the field of activity-dependent gene expression, rapid progress is being made that can impact these, and many other areas of neuroscience. This book offers an up-to-date picture of the field.
Ancient and Medieval Theories of Intentionality
This volume analyses ancient and medieval theories of intentionality in various contexts: perception, imagination, and intellectual thinking. It sheds new light on classical theories (e.g. by Aristotle and Thomas Aquinas) and examines neglected sources, both Greek and Latin. It includes contributions by J. Biard, M. Burnyeat, V. Caston, D. Frede, R. Gaskin, E. Karger, C. Michon, D. O'Meara, C. Panaccio, R. Pasnau, D. Perler, Ch. Rapp, P. Simons, R. Sorabji, and H. Weidemann.
Memory and Emotion
Deals primarily with the role of emotions in the mechanisms of memory. A compilation of the lectures given at a course conducted at the International School of Biocybernetics.
The Postmodern Brain
This interdisciplinary work discloses an unexpected coherence between recent concepts in brain science and postmodern thought. A nonlinear dynamical model of brain states is viewed as an autopoietic, autorhoetic, self-organizing, self-tuning eruption under multiple constraints and guided by an overarching optimization principle which insures conservation of invariances and enhancement of symmetries. The nonlinear dynamical brain as developed shows quantum nonlocality, undergoes chaotic regimes, and does not compute. Heidegger and Derrida are appropriated as dynamical theorists who are concerned respectively with the movement of time and being ("Ereignis") and text ("Differance"). The chasm between postmodern thought and the thoroughly metaphysical theory that the brain computes is breached, once the nonlinear dynamical framework is adopted. The book is written in a postmodern style, making playful, opportunistic use of marginalia and dreams, and presenting a nonserial surface of broken complexity. (Series A)
Recent Advances In Density Functional Methods, Part Ii
Of all the different areas in computational chemistry, density functional theory (DFT) enjoys the most rapid development. Even at the level of the local density approximation (LDA), which is computationally less demanding, DFT can usually provide better answers than Hartree-Fock formalism for large systems such as clusters and solids. For atoms and molecules, the results from DFT often rival those obtained by ab initio quantum chemistry, partly because larger basis sets can be used. Such encouraging results have in turn stimulated workers to further investigate the formal theory as well as the computational methodology of DFT.This Part II expands on the methodology and applications of DFT. Some of the chapters report on the latest developments (since the publication of Part I in 1995), while others extend the applications to wider range of molecules and their environments. Together, this and other recent review volumes on DFT show that DFT provides an efficient and accurate alternative to traditional quantum chemical methods. Such demonstration should hopefully stimulate frutiful developments in formal theory, better exchange-correlation functionals, and linear scaling methodology.
Protein Kinase C
Protein kinase plays a major role in cellular function and regulation, controlling many cellular processes. In addition to its involvement in cellular processes, the molecular and regulatory properties of the enzyme are discussed in this volume.
