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In the analytical introduction to the calendar, the authors discuss the physical characteristics and locations of the theatres; their acoustics and capacities; the Dublin theatre season; composition, administration, and management of the companies of performers; management styles and techniques; actors' contractual arrangements, conditions, and salaries; ticket prices; benefit and command performances; the composition of the repertory; costumes, scenery, wardrobe, and machinery, and much else. Special attention is paid to areas that have been neglected by previous histories, such as dance and dancers, and prologues and epilogues.
Many sedimentary basins worldwide contain extrusive and intrusive igneous rock sequences, and these rocks and associated magmatic processes can exert profound influences on a diverse range of basin processes and elements, including multiscale structural and tectonic development, heat flow, transport of hydrocarbons and other basinal fluids, and the hydraulic properties and integrity of reservoir and sealing units. Recent years have witnessed increased focus on improved understanding of igneous processes in basins to aid hydrocarbon exploration and development projects, and there is growing interest in the multifaceted role that igneous sequences in basins may play in the energy transition, f...
Vol. 1-36 (1879-1914) give statistics for 1878-1913.
Vols. for 1963- include as pt. 2 of the Jan. issue: Medical subject headings.
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Fungal and parasitic diseases affect more than one billion people across the globe. This is one-sixth of the world´s population, mostly located in developing countries. The lack of effective and safe treatments, combined with inefficient diagnosis, leads to serious chronic illness or even death. There is a discrepancy between the rate of drug resistance and the development of new medicines. Formulation of antifungal and antiparasitic drugs adapted to different administration routes is challenging, bearing in mind the poor water solubility that limits their bioavailability and efficacy. There is an unmet clinical need to develop vaccines, novel formulations and drug delivery strategies that can improve the bioavailability and therapeutic effects by enhancing their dissolution, increasing their chemical potency, stabilizing the drug and targeting high concentrations of the drug to infection sites. This Special Issue includes ten research articles of antifungal and antiparasitic drug delivery systems.
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Rosai and Ackerman’s Surgical Pathology delivers the authoritative guidance you need to overcome virtually any challenge in surgical pathology. Recognized globally for his unmatched expertise, preeminent specialist Juan Rosai, MD brings you state-of-the-art coverage of the latest advancements in immunohistochemistry, genetics, molecular biology, prognostic/predictive markers, and much more - equipping you to effectively and efficiently diagnose the complete range of neoplastic and non-neoplastic entities. Efficiently review the clinical presentation, gross and microscopic features, ultrastructural and immunohistochemical findings, differential diagnosis, therapy, and prognosis for virtuall...
The zebrafish (Danio rerio) is a valuable and common model for researchers working in the fields of genetics, oncology and developmental sciences. This full-color atlas will aid experimental design and interpretation in these areas by providing a fundamental understanding of zebrafish anatomy. Over 150 photomicrographs are included and can be used for direct comparison with histological slides, allowing quick and accurate identification of the anatomic structures of interest. Hematoxylin and eosin stained longitudinal and transverse sections demonstrate gross anatomic relationships and illustrate the microscopic anatomy of major organs. Unlike much of the current literature, this book is focused exclusively on the zebrafish, eliminating the need for researchers to exclude structures that are only found in other fish.