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Molecular pharmacological approaches against lung diseases: targeted drug discovery
Molecular Pharmacological approaches against lung diseases: targeted drug discovery The global burden of lung diseases is rising continuously and is a constant concern. Lung diseases of concern, including asthma, infection (pneumonia), lung cancer, abnormal build-up of fluid, swelling, and inflammation, both neoplastic and non-neoplastic diseases, are listed as the third leading cause of death by the World Health Organization. The most common disease in the lungs includes asthma, cystic fibrosis, chronic obstructive pulmonary disease etc. The respiratory issues listed here, among others, are exacerbated by environmental toxicants which directly come in contact with the lung architecture thereby causing lung pathologies resulting in the exacerbated immune response in affected patients. Biologically active molecules including small or large molecular weight compounds from natural or synthetic sources exhibit prominent pharmacological properties that impact health by modulating disease pathophysiology, and influence the ligand-receptor interactions, depending upon the pathway and their bioavailability.
Allergic Asthma Immunopathogenesis
Asthma is a chronic complicated airway disease whose mortality and morbidity rates have increased worldwide. Some common treatments for asthma cannot control it nor even prevent simple inflammation and relieve shortness of breath, so understanding its molecular pathways and pathophysiology is required in order to better understand the disease and to diagnose, control and treat it. Allergic Asthma Immunopathogenesis: Immunopathology of the Allergic Asthma presents a new glance to the allergic asthma pathophysiology by focusing on the immunopathogenesis and allergo-inflammation mechanisms of asthma and cell signaling pathways that can be used for various research purposes, including the design of anti-asthma treatment and target therapy for scientists and researchers. - Covers new molecular pathophysiology mechanisms and cell signaling pathways in pathogenesis of allergic asthma that have been introduced in recent research - Discusses immunologic basis of the allergy and hyperresponsiveness - Includes results of recent research focusing on the diagnosis and treatment of allergic asthma
Dietary Polyphenols in Human Diseases
Diets rich in plant polyphenols or dietary polyphenols are the subject of increasing scientific interest because of their diverse range of health benefits and medicinal uses. This book, Dietary Polyphenols in Human Diseases: Advances and Challenges in Drug Discovery, fills the gap that exists in the current knowledge by presenting the latest information in the area of polyphenol-based drug discovery research. The book focuses on the current understanding of the beneficial effects on human health of diets rich in polyphenols and/or polyphenolic compounds derived from dietary sources (plant-based foods) and their possible preventive role in the management of chronic human diseases. In addition...
Paving the Path to Discoveries and Unlocking the Secrets of N-Heterocycles
This book is a groundbreaking exploration of N-heterocycles, encompassing their historical significance, current prospects, and diverse biological applications. The book's primary objectives are to unravel the historical evolution of N-heterocycles, elucidate their contemporary relevance, and investigate their crucial role in various scientific domains. This book fills a substantial knowledge gap by offering a holistic perspective on N-heterocycles, fostering a profound understanding of their diverse applications, inspiring future research directions, and serving as a vital educational resource. It employs a multifaceted approach, including historical analysis, literature review, case studie...
Coronavirus Drug Discovery
Coronavirus Drug Discovery, Volume 1: SARS-CoV-2 (COVID-19) Prevention, Diagnosis, and Treatment is the first of three volumes presenting comprehensive information on drug discovery against COVID-19. This volume provides background information on the genesis of COVID-19, the epidemiology, transmission, pathogenesis, and mutagenesis. It also presents the various treatment options, drug discovery opportunities and vaccine developmental processes. Written by global team of experts from key institutions across the globe, this book is recommended to all concerned agencies, private research firms, and consortiums working on finding a solution to COVID-19 and its variants. By design, this book will be useful to drug developers, medicinal chemists, pharmacologists, health experts, researchers, students and faculty members in industry and academia. - Presents information on the genesis of COVID-19, global impact and collaborative efforts - Details the epidemiology, transmission, pathogenesis, and mutagenesis of SARS-CoV-2 - Documents the various treatment options and vaccine development for COVID-19
Ethnopharmacology
Ethnopharmacology is one of the world’s fastest-growing scientific disciplines encompassing a diverse range of subjects. It links natural sciences research on medicinal, aromatic and toxic plants with socio-cultural studies and has often been associated with the development of new drugs. The Editors of Ethnopharmacology have assembled an international team of renowned contributors to provide a critical synthesis of the substantial body of new knowledge and evidence on the subject that has emerged over the past decade. Divided into three parts, the book begins with an overview of the subject including a brief history, ethnopharmacological methods, the role of intellectual property protectio...
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