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New Trends in Cancer for the 21st Century
Given the latest advances in cancer research, which includes basic research and its derived diagnostic, clinical, and therapeutic applications, the book New Trends in Cancer for the 21st Century is written by individuals such as molecular biologists, whose tasks are to decipher, after sequencing the human genome, those new genes and pathways involved in the carcinogenesis process; clinical and molecular pathologists, who apply these discoveries for the molecular diagnosis and characterization of the tumor; and clinical oncologists, who treat patients. Pharmacogenetics introduces new perspectives in the translational fields with the design of drugs against specific targets, which at this moment are in clinical trials phases. This book achieves a state of the art in every field of cancer research and discusses the new perspectives that will open the future for cancer treatment (basic research, new technologies, new drugs, therapies...). For this reason, the book is intended for pathologists, clinicians, and biologists, as well as fellows and students of physiology and medicine.
Advances in Immunology
Advances in Immunology presents current developments as well as comprehensive reviews in immunology. Articles address the wide range of topics that comprise immunology, including molecular and cellular activation mechanisms, phylogeny and molecular evolution, and clinical modalities. Edited and authored by the foremost scientists in the field, each volume provides up-to-date information and directions for future research. - Interactions between NK Cells and B Lymphocytes - Multitasking of helix-loop-helix proteins in lymphopoiesis - The pathogenesis of Diabetes in the NOD Mouse
Dendritic Cells
Dendritic Cells, Second Edition is the new edition of the extremely successful book published in 1998. With the volume of literature on dendritic cells doubling every year, it is almost impossible to keep up. This book provides the most up-to-date synthesis of the literature, written by the very best authors. It is essential reading for any scientist working in immunology, cell biology, infectious diseases, cancer, transplantation, genetic engineering, or the pharmaceutical/biotechnology industry.An entirely new section on DC biology is included in this edition. Also new to this edition are chapters on: - Imaging - Interaction of dendritic cells with viruses - Dendritic cells and dendrikines, chemokines and the endothelium - Molecules expressed in dendritic cells - Role of dendritic cells in wound healing and atherosclerosis - Delivery of apoptotic bodies - Genetic engineering of dendritic cells - Imaging - Practical aspects of clinical protocol development
Tumor Immunology and Immunotherapy - Cellular Methods Part B
Tumor Immunology and Immunotherapy - Cellular Methods Part B, Volume 632, the latest release in the Methods in Enzymology series, continues the legacy of this premier serial with quality chapters authored by leaders in the field. Topics covered include Quantitation of calreticulin exposure associated with immunogenic cell death, Side-by-side comparisons of flow cytometry and immunohistochemistry for detection of calreticulin exposure in the course of immunogenic cell death, Quantitative determination of phagocytosis by bone marrow-derived dendritic cells via imaging flow cytometry, Cytofluorometric assessment of dendritic cell-mediated uptake of cancer cell apoptotic bodies, Methods to assess DC-dependent priming of T cell responses by dying cells, and more.
Immunogenic Cell Death in Cancer: From Benchside Research to Bedside Reality
Classically, anti-cancer therapies have always been applied with the primary aim of tumor debulking achieved through widespread induction of cancer cell death. While the role of host immune system is frequently considered as host protective in various (antigen-bearing) pathologies or infections yet in case of cancer overtime it was proposed that the host immune system either plays no role in therapeutic efficacy or plays a limited role that is therapeutically unemployable. The concept that the immune system is dispensable for the efficacy of anticancer therapies lingered on for a substantial amount of time; not only because evidence supporting the claim that anti-cancer immunity played a rol...
Natural Killer Cells
Natural killer (NK) cells have been at the forefront of immunology for two decades. During that time, a great amount of information about these cells has been obtained. They are important in antiinfectious and antitumoral defense and shape the adaptive immune response. In addition, they can act as immunoregulatory cells. In recent years, the therapeutic potential of NK cells in cancer immunotherapy has become increasingly evident. This book describes in detail current knowledge about NK cells and covers a broad range of NK cell-related topics, including those that are not frequently reviewed, e.g. NK cells and allergy or NK cells and skin diseases.
Gut Feelings
Why the microbiome--our rich inner ecosystem of microorganisms--may hold the keys to human health. We are at the dawn of a new scientific revolution. Our understanding of how to treat and prevent diseases has been transformed by knowledge of the microbiome—the rich ecosystem of microorganisms in and on every human. These microbial hitchhikers may hold the keys to human health. In Gut Feelings, Alessio Fasano and Susie Flaherty show why we must go beyond the older, myopic view of microorganisms as our enemies to a broader understanding of the microbiome as a parallel civilization that we need to understand, respect, and engage with for the benefit of our own health. Recent advances in under...
神奇的外泌體
外泌體如同雞精，而幹細胞就像雞湯 在濃度和效果上，雞精更勝雞湯 ——杜元坤高雄義大醫院院長 ｛為何外泌體被稱為再生醫學的新希望 ？} ◎ 奈米級分子：分子結構小，易於吸收，生物相容性高。 ◎ 雙層脂質膜結構：可保持生物活性，帶來再生修復作用。 ◎ 訊息載體機制：訊息分子變化反映來源細胞的生理及功能狀況，幫助疾病診斷與治療。 ◎ 高穩定度、精準靶向性：穩定且可全身循環，組織穿透性強，是藥物載體的理想選擇。 ◎ 應用範圍廣泛：從疾病診斷治療、醫藥保健到抗老護膚，影響及成效顯著。 外泌體由...
Cancer Vaccines
With ten million persons afflicted each year, no one is entirely immune to cancer and its devastating effects on individuals and families. But recent advances in the development of cancer vaccines—either as therapeutic agents or as preventative measures—are hopeful indicators of progress in this field. This volume comprises invited chapters from world-renowned researchers and clinicians that shed light on recent steps forward in immunotherapeutic and preventive approaches for future cancer vaccines. NOTE: Annals volumes are available for sale as individual books or as a journal. For information on institutional journal subscriptions, please visit www.blackwellpublishing.com/nyas. ACADEMY MEMBERS: Please contact the New York Academy of Sciences directly to place your order (www.nyas.org). Members of the New York Academy of Science receive full-text access to the Annals online and discounts on print volumes. Please visit http://www.nyas.org/MemberCenter/Join.aspx for more information about becoming a member.
