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Never Bet Against Occam
In 2008 Dr. Afrin started coming to understand that a newly recognized type of mast cell disease, now called mast cell activation syndrome (MCAS), was the underlying diagnosis in many patients he was seeing who were each suffering large assortments -- quite different from one patient to the next -- of chronic multisystem inflammatory illnesses of unclear cause. Dr. Afrin soon gained experience that MCAS is far more prevalent than the only mast cell disease previously known to medicine (the rare disease of mastocytosis) and that most MCAS patients, once accurately diagnosed, can eventually find significantly helpful medications targeted at the disease. The frequency and magnitude of the impro...
Never Bet Against Occam: Mast Cell Activation Disease and the Modern Epidemics of Chronic Illness and Medical Complexity
In 2008 Dr. Afrin started coming to understand that a newly recognized type of mast cell disease, now called mast cell activation syndrome (MCAS), was the underlying diagnosis in many patients he was seeing who were each suffering large assortments ? quite different from one patient to the next ? of chronic multisystem inflammatory illnesses of unclear cause. Dr. Afrin soon gained experience that MCAS is far more prevalent than the only mast cell disease previously known to medicine (the rare disease of mastocytosis) and that most MCAS patients, once accurately diagnosed, can eventually find significantly helpful medications targeted at the disease. The frequency and magnitude of the improve...
Mast Cells United: A Holistic Approach to Mast Cell Activation Syndrome
At 542 pages and referencing over 1200 academic articles, this book is the longest and most thorough resource on mast cell activation syndrome (MCAS) to date. Allergies and anaphylaxis are on the rise, alongside gastrointestinal problems, skin issues, fatigue, orthopedic pain, neurological symptoms, and just about everything in between. Patients are coming out of the woodwork with chronic, debilitating, often invisible illness. Recent research estimates that 14%-17% of the population may have mast cell activation disease. Much of the medical community has never heard of the condition, and existing mainstream treatment tends to focus predominantly on pharmacological management. However, once ...
Mast Cells
Resident mast cells are uniquely positioned in multiple organ systems at either the tissue and/or external environment or located near nerve endings and/or blood vessels. These locations allow the mast cell to serve as a sentinel and thus play a critical role in not only inflammatory situations to promote recruitment and infiltration of other immune cells, but also homeostatic maintenance. Although mast cells have several conserved characteristics, the authors provide evidence that the micro-environment influenced differences in the phenotype of tissue-specific mast cells, control the various responses to injury, inflammation and remodelling. This book brings together the work from experts across multiple tissue/organ systems and inflammatory causes (viral, bacterial, and auto-immune) to present the most up to date knowledge regarding the role of mast cells in these regulatory and disease events.
E-Health and Telemedicine: Concepts, Methodologies, Tools, and Applications
Advances in medical technology increase both the efficacy and efficiency of medical practice, and mobile technologies enable modern doctors and nurses to treat patients remotely from anywhere in the world. This technology raises issues of quality of care and medical ethics, which must be addressed. E-Health and Telemedicine: Concepts, Methodologies, Tools, and Applications explores recent advances in mobile medicine and how this technology impacts modern medical care. Three volumes of comprehensive coverage on crucial topics in wireless technologies for enhanced medical care make this multi-volume publication a critical reference source for doctors, nurse practitioners, hospital administrators, and researchers and academics in all areas of the medical field. This seminal publication features comprehensive chapters on all aspects of e-health and telemedicine, including implementation strategies; use cases in cardiology, infectious diseases, and cytology, among others; care of individuals with autism spectrum disorders; and medical image analysis.
The Trifecta Passport: Tools for Mast Cell Activation Syndrome, Postural Orthostatic Tachycardia Syndrome and Ehlers-Danlos Syndrome
The “trifecta” refers to three conditions that commonly occur together: mast cell activation syndrome (MCAS), postural orthostatic tachycardia syndrome (POTS) and the hypermobile type of Ehlers-Danlos syndrome (hEDS). These three conditions are gradually becoming more recognized in the mainstream medical world as more and more patients find themselves struggling with debilitating and often mysterious symptoms. However, recognizing these conditions is only the first step on the healing journey. With the right approach and toolbox, patients can reverse many of these symptoms to find lasting vitality. Written by a Doctor of Physical Therapy who has additional certifications in functional me...
Constant Vigilance
"The condition upon which God hath given liberty to man is eternal vigilance; which condition if he breaks, servitude is at once the consequence of his crime and the punishment of his guilt." Exactly who first uttered this phrase is somewhat in dispute. It has been attributed to a number of the founding fathers of the United States. This phrase has more relevance today than at any time in the history of the United States or in the history of Mankind. Not only do we need to guard our liberty from the abuse of the power and authority that we have granted to our government, we also need to guard against the abuse of power garnered by multinational corporations. This story chronicles the development of Constant Vigilance in an ordinary guy who by happenstance finds himself in the cross hairs of powerful forces determined to control and prevent the spread of information that may harm their interest. The circumstances he stumbles into threaten his safety and his way of life. His path to understanding tests his beliefs and relationships. In the final analysis, the road less traveled may be the only option left.
Medusa's Clot
It will kill about 50-100,000 Americans in the next 12 months and most will never "see" it coming. By the time one Googles "The clot in my lung," 10% will die before the webpage is fully loaded and that is with a speedy WIFI connection. Medusa's Clot discusses from lamb to loom a disease of which 80% of people are unaware. Hard to believe as there are approximately 4.9 million Internet hits on the subject. It is known as PE, short for pulmonary embolism. The book also discusses peripherally the deracinated healthcare system along with the roles of science and faith in disease and in health. The subject which is couched in humor, spirituality, and history brings to life an entity that surreptitiously continues as Mary Shelly had written in Frankenstein, "To glut the maw of death."
An Introduction to Clinical Emergency Medicine
Fully-updated edition of this award-winning textbook, arranged by presenting complaints with full-color images throughout. For students, residents, and emergency physicians.
Histamine Intolerance
Histamine is an important mediator of allergic diseases, but knowledge of histamine as a cause of numerous non-allergic symptoms and signs is limited. This book offers wide-ranging coverage of histamine intolerance. There is extensive background discussion of the origin of histamine, its content in food and alcoholic beverages and intolerance to red wine. Diagnosis of histamine intolerance is explained and the various symptoms of histamine intolerance are clearly described. Subsequent chapters cover the relation of histamine to a wide variety of conditions, including drug intolerance, atopic dermatitis, seasickness and osteoporosis. This book will prove of value in clinical practice by facilitating differential diagnosis, which is by no means straightforward given the multiplicity of symptoms of histamine intolerance and by assisting in the selection of therapeutic measures.
