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Tailoring treatment for individual breast cancers is no longer a dream and is now the main goal for current research. This book gives an overview of the most recent techniques, agents and approaches for breast cancer and the individualization of treatment. Particular attention is given to organ-specific tailored approaches, specific populations, patients’ preferences and rehabilitation. Contributions from experts focus on the biomedical research behind the transfer of molecular biology knowledge into the clinical management of patients. This has led to increased survival as well as improved quality of life. The book gives an overview of the latest achievements in breast cancer and their use in clinical practice.
Contributions from leading authors in the field of clinical and biological breast cancer research constitute these three chapters: predisposition to breast cancer, carcinogenesis, and early breast cancer screening and management; tumour biology and prognostic; and therapeutics aspects of breast cancer. 21st Meeting of the International Association for Breast Cancer Research, Paris, 1996.
Completely revised and updated, and now in full color throughout, the Fourth Edition of this definitive reference is a must for all clinicians who treat breast diseases. Leading experts summarize the current knowledge of breast diseases, including their clinical features, management, underlying biologies, and epidemiologies. In addition to complete coverage of malignant breast diseases, benign diseases are discussed in relation to subsequent breast cancer development. The book reviews all major clinical trials and summarizes the information they provide on early detection and management of breast cancer. Close attention is also given to the increasing importance of molecular biology and gene...
The complex landscape of breast cancer requires distinct strategies for the management of various molecular subtypes of this disease. Rapid advances in the field of molecular biology have been bewildering for those involved in its study and management. “Molecular Pathology of Breast Cancer” aims to close this knowledge gap by discussing comprehensively the evolution, biological basis and clinical applications with a focus on the “what, when, and how” of the most significant molecular markers known to date. These markers are evaluated in the context of genomic, transcriptomic and proteomic profiles, which is integral to the practice of precision medicine. The application of next gener...
This definitive, up-to-the-minute reference explores the range of metabolic, nutritional, immunologic, and psychological changes that can occur while treating local, regional, and distant cancer, and examines the influence of these factors on outcomes and recovery. Includes clearly written, concise summaries of oncological therapy emphasizing c
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The latest advances in Artificial Intelligence and (deep) Machine Learning in particular revealed a major drawback of modern intelligent systems, namely the inability to explain their decisions in a way that humans can easily understand. While eXplainable AI rapidly became an active area of research in response to this need for improved understandability and trustworthiness, the field of Knowledge Representation and Reasoning (KRR) has on the other hand a long-standing tradition in managing information in a symbolic, human-understandable form. This book provides the first comprehensive collection of research contributions on the role of knowledge graphs for eXplainable AI (KG4XAI), and the p...